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Irritable Bowel Syndrome (IBS) Message Board

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    Old 07-24-2018, 05:56 AM   #1
    Jwilliams74d's Avatar
    Join Date: Jul 2018
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    Jwilliams74d HB User
    My Solution

    After 6 months of symptoms with no relief my doctor put me on 25mg of Desipramine. Symptoms are 95% gone for over a week now. A complete 180.

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    Old 07-24-2018, 01:56 PM   #2
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    dac122 HB User
    Re: My Solution

    Glad it is working for you. What were your symptoms and why did your doc decide on an antidepressant since those tend to cause GI issues?

    Last edited by dac122; 07-24-2018 at 01:57 PM.

    Old 07-24-2018, 02:04 PM   #3
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    Re: My Solution

    I was having stomach pains, gurgling and diarrhea about 5 times a day. A normal dose for Desipramine is 100-200mg for depression but appearantly when administered in low doses 15-25mg it is helpful with ibs-d symptoms.

    Old 03-08-2019, 10:58 PM   #4
    louiisse's Avatar
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    Re: My Solution

    I've been on Imipramine, which I believe is in the Desipramine family, for 10 of the 19 yrs I've had IBS-D. It's a low dose and it has done wonders for the diarrhea. It doesn't completely stop it so I add one or two Imodium. This combination for me has quickened the healing process. I also drink an herbal bed time tea which seems to help calm my colon. Hope this info might help you.


    Last edited by louiisse; 03-08-2019 at 10:59 PM.

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