It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....

Lung & Respiratory Disorders / COPD Message Board

  • Latent TB

  • Post New Thread   Closed Thread
    Thread Tools Search this Thread
    Old 06-18-2007, 03:15 PM   #1
    Junior Member
    Join Date: Jun 2007
    Location: Northport, AL USA
    Posts: 14
    daddymatt HB User
    Cool Latent TB

    Hello All-
    I am new to this board, but have posted some things about my fledgling attempts to quit smoking on another thread.
    I did not see a thread for TB in here anywhere. Maybe I missed it. It is an important topic, but not the panic inducing one that most people think it is.
    Anyhow, I have been diagnosed with latent TB for 6 years now. I have always been asymptomatic, but get a regular chest xray just in case (annually). I went on INH when I was first diagnosed, but went toxic after about 3 months, and had to stop. Liver tests were off the chart, and I felt like I had permanent flu all day, every day for 90 days. Not everyone has issue like I had, but it was hell.
    Anyhow, anyone else out there who is dealing with latent TB? It can be scary when you first hear about it. I still have my moments, especially when the media goes insane and people get all hyped up.
    I thought we could "chat" and maybe support others who may need it, as well as help each other along the way.
    Thanks...hope to hear from some of you soon.

    Sponsors Lightbulb
    Old 07-14-2007, 06:20 AM   #2
    roxcyn's Avatar
    Join Date: Apr 2004
    Posts: 466
    roxcyn HB Userroxcyn HB Userroxcyn HB Userroxcyn HB Userroxcyn HB Userroxcyn HB User
    Re: Latent TB

    I believe there are other TB drugs that can be taken, they are listed on **** just search for tuberculosis.

    Actually that is good that you are trying to be active about it, but you may want to talk to a doctor about taking one of the other drugs.

    Old 09-02-2007, 08:42 PM   #3
    Senior Member
    Join Date: Jul 2007
    Location: PA
    Posts: 181
    peacefrog HB User
    Re: Latent TB

    My grandaughters other grandma has just been diagnosed with TB. She had surgery for lung cancer this week and they just found the TB. I don't know any other details, but am concerned about the contact my grand(6 mo) has had with her. How contagious is it, and how serious a condition is it for someone in a weaken state like her grandmother? Thanks in advance for any info. I don't want to burden her family with alot of questions, they have alot on their minds right now.

    Old 09-06-2007, 01:11 PM   #4
    Join Date: May 2007
    Location: west falls, ny u.s.
    Posts: 83
    linda71 HB User
    Re: Latent TB

    I talked to my physician yesterday because my biopsy came back with TB too. I am not overly sick and I have so many other lung diseases. She said that I was not contagious to my grandchildren which was a relief. It is scarey when they say TB. I don't know very much about Latent TB. I would love to here anything you find out.

    Old 10-18-2007, 12:21 PM   #5
    Junior Member
    Join Date: Oct 2007
    Location: USA
    Posts: 27
    Rheinau HB User
    Re: Latent TB

    I found out I have latent TB in late June. 9mm. My Primary doc says to hold off on the meds since I am low risk for active TB. My pulmonoligist says to take them ASAP. The health dept says to wait and get retested in a year and then reevaluate.

    Daddymatt - there are other meds for latent TB but the risk for liver injury is as high as INH. If you have already taken 3 months worth you have some protection per the CDC website. Just curious - how old are you? I have read that side effects are more common the older you get and also if you have a history of drinking. I am 40 and drank for years but stopped 18 months ago. I am nervous about the INH.

    There are some new drugs being developed - PA 824 and FAS 20013 but they are at least 2-3 years out. I guess my timing was bad.

    I plan to give the INH a shot but am not happy about the whole thing. I was totally freaked out for about 2 months after finding out about the TB but I guess I went through the grief stages and have accepted it - I don't have a choice.

    Old 10-20-2007, 04:20 AM   #6
    Join Date: Oct 2007
    Location: uk
    Posts: 1
    jackyb HB User
    Re: Latent TB

    Dear all,

    Just been diagnosed with LTBI - Clear Chest Xray and a "doubtful Positive" result on the QTF-Gold test.

    ESAT6 = 0
    CFP-10 = 0.2

    They are recommending INH for 6 months ( I am living in Japan) but I would obviously prefer not to take this.
    Does anyone have any exprience of treatment advice with these levels of test results?

    Many thanks guys and gals,


    Old 10-20-2007, 07:51 AM   #7
    Junior Member
    Join Date: Oct 2007
    Location: USA
    Posts: 27
    Rheinau HB User
    Re: Latent TB

    jackyb - I am not familiar with the QTF-Gold test results. Mine was a PPD test. Have you taken a PPD? Maybe you should also take a PPD test.

    I think the QTF only reacts to the TB bacteria and the PPD reacts to both TB and non-TB mycrobacteria.

    With respect to taking INH, the whole thing is a gamble. Overall a 10% chance of active TB without treatment. Based on studies I've read 6 months of INH offers a medium level of protection with a more significant level from the 9 month course.

    I know one person (a non-drinker) who took 9 months of INH while in her mid 30s with no problems at all. Based on the studies I have read, there is a 1% chance of hepatitis. With monthly liver function tests, I am sure this is reduced. For those who have LFT with elevations 2-3 times normal, they are normally taken off the meds.

    I will probably go on the meds although I am considered a low risk for going active. I have children and I don't want to risk infecting them. My primary care provider recommends I don't go on the meds, my pulmonary doc recommends I go on the meds ASAP. If you go on the meds you need to take Vitamin B-6 25mg per day to help prevent neuropathy.

    There are articles out that say vitamin d helps the body fight the TB bacteria, but I did some research on the dosage and it was 2.5mg every 6 weeks which equals about 250 times the recommended allowance of vitamin d. There may be some issues with toxicity. I am just going to take 800 IU (400 IU is the recommended dose for most folks) of vitamin d a day and hope for the best.

    I guess the best thing we can do is stay healthy. Moderate exercise, good food, and plenty of rest are our best weapons until they come out with safer meds - 3 or so years from now.

    Good luck with it. Keep us posted.

    The CDC website offers a number of articles about the LTBI treatment:


    Old 11-09-2007, 03:03 PM   #8
    Pri Lily
    Join Date: Sep 2007
    Location: Canada
    Posts: 1,096
    Pri Lily HB User
    Re: Latent TB

    Hi Everybody....

    I would suggest a second opinion before going on INH.

    My story....

    Going to school....PPD came back positive 14mm induration....bye bye school.

    Had a chest x-ray...clear...

    Had another PPD....10mm induration.....sputum samples...clear...

    Had a bronchoscopy...and more sputum samples.....clear

    Went on INH therapy....I am on other psychotropic drugs, and have a very delicate system. The INH interacted with my other drugs, I got every side effect, in the book, and had a few that they didn't know about. Had peripheral neuropathy the first night...woke up with stabbing pain in my foot, and then my leg would fly up into the air. I was taking B6.

    Was taken off the INH after four days, because I was O/Ding, and it was getting worse every day.

    I'm now being sent to another hospital, which specializes in TB to be evaluated.

    I have been advised to take drug therapy, but nobody knows what will work without making me O/D..

    Giving up the other meds is out of the question.

    This has been an 11 month far.....

    I would go with the opinion of Public Health, personally.


    Last edited by moderator2; 11-09-2007 at 03:16 PM.

    Old 11-14-2007, 08:22 AM   #9
    Junior Member
    Join Date: Oct 2007
    Location: USA
    Posts: 27
    Rheinau HB User
    Cool Re: Latent TB

    My TB reaction was 9mm in Aug. Was retested a couple of weeks ago - 20mm. Started the INH a week ago. The first day had nausea but it appears due to the fact that it was 5 hours since eating. Had some tingling in my left hand the first few days but bought some B6 50 mg and it hasn't returned.

    Today is my 7th dose of INH. So far so good. I take the med exactly 2 hours after eating breakfast. According to what I've read, taking with food neutalizes the meds.

    Seems as though I get a little "loopy" the first hour after taking the med. After that no issues. I am taking milk thistle in the morning and evening - hopefully it will help my liver.

    Also taking multivitamin in the early morning. Take the B6 and also vit D 800IU in the evening.

    I was extremely anxious about INH but was also anxious about the TB bacteria. I am happier since I started taking the INH. Hopefully it will kill the bacteria and not be too rough on my liver.

    Last edited by Rheinau; 11-14-2007 at 08:26 AM.

    Closed Thread

    Related Topics
    Thread Thread Starter Board Replies Last Post
    Isoniazid Therapy (INH) for latent TB concerns wildflower73 Infectious Diseases 18 08-08-2011 07:36 AM
    Eales disease and latent tuberculosis Gauri101 Eye & Vision 0 10-05-2009 09:47 PM
    latent TB -- should I worry? Hacamila Lung & Respiratory Disorders / COPD 0 04-05-2009 04:11 PM
    latent virus returns or decompensation event ? elpirata Inner Ear Disorders 1 06-14-2006 09:13 AM
    Latent Tuberculosis...Should I worry? micro Lung & Respiratory Disorders / COPD 2 05-02-2006 02:52 PM
    Latent TB & Drug side effects aum Infectious Diseases 4 01-17-2005 06:52 PM
    Latent TB crabbycdn Lung & Respiratory Disorders / COPD 15 01-18-2004 12:00 PM

    Thread Tools Search this Thread
    Search this Thread:

    Advanced Search

    Posting Rules
    You may not post new threads
    You may not post replies
    You may not post attachments
    You may not edit your posts

    BB code is On
    Smilies are On
    [IMG] code is Off
    HTML code is Off
    Trackbacks are Off
    Pingbacks are Off
    Refbacks are Off

    Sign Up Today!

    Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

    I want my free account

    All times are GMT -7. The time now is 08:29 PM.

    2019 MH Sub I, LLC dba Internet Brands. All rights reserved.
    Do not copy or redistribute in any form!