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Old 03-21-2004, 08:17 PM   #1
Join Date: Jan 2001
Location: Madison, WI
Posts: 144
renae HB User

Have any of you currently taking any immunosuppressants had an abnormal pap smear for the first time? I've never, ever had one before and do get one every year. I just found out that my last one was abnormal--very. I'm due to have a colposcopy in a couple of weeks.

After doing some reasearch, I discovered that immunosuppressants can cause abnormal paps and cervical cancer! I don't have any of the other risks factors; multiple sex partners, sexual active at young age, etc. But I am on several immunosuppressants; prednisone, cellcept, plaquenil, methotrexate.
Just wondering if anyone else has had this come up?

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Old 02-15-2006, 09:31 PM   #2
Join Date: Apr 2005
Location: Beautiful West Virginia
Posts: 27
Langoley HB User
Re: Immunosuppressants

Yes, I've been having abnormal paps for the past 5-6 years. Try not to panic. I'm not sure if it's the meds or the Lupus itself changing the cells on the cervix. I've had the colposcopy and my GYN also did some "scraping" off "bad" cells off of the cervix. I get paps every 6 months and she always uses the Thin Prep type slides. They give her a more accurate reading on the cervical cells. Nothing I've had is precancerous; simply "malformed". Dr., says it can be a precourser for cancer if you don't watch things. That said, I'm OK so far and as bad as this Lupus gets sometimes, Cancer doesn't really scare me anymore
Best of luck to you,

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