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Trouble taking Lupus drugs??

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Old 03-07-2006, 09:09 AM   #1
Join Date: Aug 2003
Location: half moon bay, california. U.S.A.
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caroleye HB User
Trouble taking Lupus drugs??

Several years ago, I had too many side affects to continue on Plaquenil.

Now I'm thinking I need to revisit a rheumy after all these years to see if there are other options, or ways to tolerate.

Curious what you're taking & if you've had difficulty; your solution, etc.

Thanks for any suggestions.


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Old 03-07-2006, 05:22 PM   #2
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Join Date: May 2003
Location: Virginia, USA
Posts: 2,347
BarbaraH HB UserBarbaraH HB UserBarbaraH HB UserBarbaraH HB User
Re: Trouble taking Lupus drugs??

Hi Carole,

What side effects bothered you with Plaquenil?

I took it twice a day for 2 years without problems, then started having increasingly frequent bouts of the runs. I tried taking it at night several months ago and was up with the runs in the middle of that night. It may be a mistake, but I'm not taking it at all now and feel okay.

My doctor did try me on the real Chloroquin, but that made no difference.

Wishing you well - Barbara

Old 03-07-2006, 06:41 PM   #3
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Re: Trouble taking Lupus drugs??

Carole, Some people here have written similarly, I think. I recall some saying they did better on brand-name Plaquenil, as opposed to generic hydroxychloroquine. And Dr. Wallace also writes in his lupus hardcover that many do indeed tolerate the name-brand better than the generic.

I had GI problems for so many years that if I indeed had any at the time I started Plaquenil, I would probably not have noticed much. I got some halo effect at night, so just avoided driving at night for a few weeks. I seem to recall being a little queasy, like you feel when you first start an antibiotic.

But the drug started helping my symptoms very quickly---mainly, fatigue, anemia, tingling, & headaches. I still have blah spells but with fewer & less severe problems. But I still need OTC pain meds fairly often.

Good luck with your decision! Take good care, Vee

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