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Blood complements

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Old 11-27-2008, 03:07 AM   #1
Join Date: Nov 2008
Location: Brisbane, QLD, Australia
Posts: 2
UnknownUCTD HB User
Blood complements

Hi all,

I don't know if anyone can help but I just cant seem to get a clear answer. My Rheumy has been treating me for SLE but can't confirm this. He has now changed it to UCTD with Fibromyalgia. I have been getting blood tests done every couple months over the last 10months. I have been on Methotrexate 25mg weekly and was on prednisone. I was doing well and my C3 C4 hit the normal limit range after several months as I was well below the lowest. Within a month of my last tests the results have jumped dramatically backwards and am well under again. I am currently at 870 for C3 (lowest is 1050) and 100 for C4 (lowest is 130) . Can anyone tell me why this has jumped so far within a month? I have been feeling very ill and in a lot of pain. I am still waiting on my ANA's to come back. I don't get to see my Rheumy until end of next month and my GP doesn't know much about it.

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Old 12-08-2008, 12:10 PM   #2
Join Date: Jul 2008
Location: birmingham,alabama
Posts: 79
pixie1985 HB User
Re: Blood compliments

Hello...I am certainly not the pro on this disease as I have only been recently diagnosed. My Rheumatoligist tells me that the complement levels rise and fall with inflammation. You did not mention if you are taking any type of medication such as Plaquenil or inflammatory meds such as Advil or Aleve. My ANA titer was in the 2400 range, Sed rate, CRP, C3, and C4 levels were elevated. He started me on Plaquenil and labs are starting to return to normal. Hope everything works out for you. Take Care. Pix

Old 12-08-2008, 11:56 PM   #3
Join Date: Nov 2008
Location: Brisbane, QLD, Australia
Posts: 2
UnknownUCTD HB User
Re: Blood compliments

Hi Pixie1985,

Sorry to hear about your condition, I am only recent myself being less than a year since diagnosis.
I am on Plaquenil, Methotrexate and Prednisone. As well as other drugs to help with the side effects from all of these. My ANA's came back within normal limits and still just as confused.... Its also strange as a everything else is within normal range too. My Dr is not keen on labelling anything at the moment so they are just treating the symptoms.

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