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    Old 06-30-2006, 01:24 PM   #1
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    Test Results positive/Liver Enzymes up?

    Hey guys..I know its just the initial screen BUT I tested positive, so I guess its on to West blot...I'm close to seeing an LLMD and get further testing for Co-infections ,etc but it unfortunately takes time. Can someone, share a high level opinion on the below, share any positives or negatives..Again, I realize its inaccuracy and lack of detail but still in all i'm curious...ALSO, I saw where 6 blues mentioned her enzyme levels were "back in range" (CONGRATS!)...Well, mine are now a bit out of range: (Alkaline Phospate 126, (ALT: 61), In the past they're always normal...Is this a normal reaction to the initial infection? I hope so..

    Below are my Labs

    Lyme D Screen: 3.68
    Interprete: Positive ABN

    Lyme Disease IgG Negative
    23 KD IgG band reactive
    41 kD IgG band reactive

    Lyme Disease (IgM) positive
    23kD IgM band reactive
    41kD IgM band reactive

    Not sure why the result reads negative for IgG when the same two numbers are bold and read "reactive"....I think it was Ticker who mentioned 41 is common with new infections but any additional insight would be appreciated prior to me getting out there and purchasing that book by Karen so and so!....Thanks, hope everyone has a great holiday weekend!!

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    Old 06-30-2006, 01:41 PM   #2
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    Re: Test Results positive/Liver Enzymes up?

    Hi smsully. I am sorry you have Lyme, but it is better to know so you can get the treatment you need.

    You ELISA looks very positive and you have positive bands on the Western Blot. Below is the breakdown:

    9 cross-reactive for Borrellia
    12 specific for Bb
    18 unknown
    20 cross-reactive for Borrellia
    21 unknown
    22 specific for Bb, probably really the 23/25 band
    23-25 outer surface protein C (OspC), specific for Bb
    28 unknown
    30 unknown; probably an outer surface protein; common in European and
    one California strain
    31 outer surface protein A (OspA), specific for Bb
    34 outer surface protein B (OspB); specific for Bb
    35 specific for Bb
    37 specific for Bb
    38 cross-reactive for Bb
    39 is a major protein of Bb flagellin; specific for Bb
    41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
    45 cross-reactive for all Borellia (sometimes people with Lyme who have
    this band positive also have the co-infection Ehrlichiosis)
    50 cross-reactive for all Borrellia
    55 cross-reactive for all Borrellia
    57 cross-reactive for all Borrellia
    58 unknown but may be a heat-shock Bb protein
    60 cross reactive for all Borrellia
    66 cross-reactive for all Borrelia, common in all bacteria
    83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
    93 unknown, probably the same protein in band 83, just migrates differently in some patients

    The IgM tests for a more recent infection and the IgG a longer-standing one. Which lab did the test? Even though the CDC requires a large number of bands to show for it to be considered positive, many people who have Lyme do not have this many bands show. Lyme doctors often focus on which bands show, some are specific for Lyme. Band 23-25 is a Lyme specific band. Your results are significant.

    Elevated liver enzymes can be a Lyme symptom. One thing that is good to take for this is Milk Thistle. It is a supplement you can get at a health food store. This should bring them back down. I suggest taking it daily.

    When will you be seeing a Lyme doctor? Was the doctor recommended by a Lyme patient?

    Old 06-30-2006, 02:44 PM   #3
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    Re: Test Results positive/Liver Enzymes up?

    Thanks Ticker...I'll be grabbibng some Milk thistle tonight since I gotta go to whole foods anyway!..I just took it upon myself to see a specialist @ the infectious Disease Dept @ Hartford Hospital, at least for the short term since a lot of people take weeks if not months for an appt...the Dir there is Brian Cooper, I would assume they're pretty good and I'm hopeful to have an appt next week as I had my pcp fax my results to them today. The test was performed by Quest Diagnostics. ..I think I was confused, help me out here, Are these results "Western blot"?..I was under the impression that was the "next test" but now it seems the screen of 3.68 was initial and the band readings on the next page was the blot, looks like it was already performed? True?...Sorry bout that...One other thing, if my IgM is positive (which would make sense) since I took the tick off a month ago, why am I showing an over-all negative for IgG, when on the report the same two bands are highlighted as reactive also?, not enough out of the 10?...Sorry if some of t his seems trivial but its a little muttling...Once again, deeply appreciated

    Old 06-30-2006, 02:57 PM   #4
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    Re: Test Results positive/Liver Enzymes up?

    Hey Ticker, After re-reading, It pretty much sunk in that the ELISA was the screen of 3.68 and the interpretation of positive...I just didn't realize they requested the Western blot which was the results on the following page w/bands...I was under the impression that had to be re-requested...Thanks again for your input, sorry bout the rambling, but no-one has yet to explain this to me so I'm sort of winging it ti'll next week....Take care!!

    Old 07-02-2006, 01:34 PM   #5
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    Re: Test Results positive/Liver Enzymes up?

    Hi smsully.

    Milk Thislte is awesome for the liver. Please spend the extra bucks to get the best quality. There are different parts of the plant used to produce this supplement and it makes a difference in the efficacy.

    I use a brand called "Pure Encapsulations". Its the most expensive, but thats probably because of the mftr costs to make it correctly. I tried other brands and they did nothing for my enzyme levels.

    Sorry to hear about the diagnosis but glad you found this site. Knowledge is power when fighting Lyme so learn all you can.

    Peace and health to you.

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