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  • My IGeneX test results.

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    Old 08-30-2007, 05:06 PM   #1
    mctassi
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    My IGeneX test results.

    I swear I'm the queen of indeterminate test results. Offically the IgeneX is Neg. but let me list the results.

    IGG
    18kda-
    22kda-
    **23-25kda-
    28kda-
    30kda-
    **31kda-
    **34kda-
    **39kda IND
    **41kda IND
    45 kda -
    58 kda +
    66kda -
    73 kda -
    **83-93 kda -

    IGM
    everything neg. except

    ** 31 kDa IND
    ** 34 kDa +

    So on the IGG I have 2 indeterminates on **39 kDa and **41 kDa
    and one positive on 58kDa
    The report says positive if 2 or more double starred bands present. IgeneX standards not CDC
    I have 2 IND on the double starred.


    IGM IGeneX pos. if 2 or more double starred bands.
    I have 1 IND
    and 1 Pos.

    I was not tested for co-infections. I talked the Doc. at the VA hospital into
    ordering the IgeneX WB test. He says I'm neg. He is an infectious disease Doc. not a LLMD.

    I was hoping to get a little further within the VA system but without offical positive results that's not going to happen.

    I know I need to see a lyme doc.

    Ticker I have a + **34kDa. That is a lyme specific band right?

    Any encouragement or advice from you great people would be appricated.

    thanks, mc

     
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    Old 08-30-2007, 06:02 PM   #2
    jenillumine
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    Re: My IGeneX test results.

    Quote:
    Originally Posted by mctassi View Post
    I swear I'm the queen of indeterminate test results. Offically the IgeneX is Neg. but let me list the results.

    IGG
    18kda-
    22kda-
    **23-25kda-
    28kda-
    30kda-
    **31kda-
    **34kda-
    **39kda IND
    **41kda IND
    45 kda -
    58 kda +
    66kda -
    73 kda -
    **83-93 kda -

    IGM
    everything neg. except

    ** 31 kDa IND
    ** 34 kDa +

    So on the IGG I have 2 indeterminates on **39 kDa and **41 kDa
    and one positive on 58kDa
    The report says positive if 2 or more double starred bands present. IgeneX standards not CDC
    I have 2 IND on the double starred.


    IGM IGeneX pos. if 2 or more double starred bands.
    I have 1 IND
    and 1 Pos.

    I was not tested for co-infections. I talked the Doc. at the VA hospital into
    ordering the IgeneX WB test. He says I'm neg. He is an infectious disease Doc. not a LLMD.

    I was hoping to get a little further within the VA system but without offical positive results that's not going to happen.

    I know I need to see a lyme doc.

    Ticker I have a + **34kDa. That is a lyme specific band right?

    Any encouragement or advice from you great people would be appricated.

    thanks, mc


    ((hugs)) it's fustrating not getting any answers
    thru tests. Its really easy to loose hope.

    My Westren Blot today came back NEG
    Quest did the testing and I think they only
    test what the CDC requires.

    Hang in there and keep fighting
    and keep hope alive.
    Jennifer

     
    Old 08-30-2007, 06:05 PM   #3
    ticker
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    Re: My IGeneX test results.

    Hi mc. Below is the breakdown of the Western Blot bands:

    9 cross-reactive for Borrellia
    12 specific for Bb
    18 unknown
    20 cross-reactive for Borrellia
    21 unknown
    22 specific for Bb, probably really the 23/25 band
    23-25 outer surface protein C (OspC), specific for Bb
    28 unknown
    30 unknown; probably an outer surface protein; common in European and
    one California strain
    31 outer surface protein A (OspA), specific for Bb
    34 outer surface protein B (OspB); specific for Bb
    35 specific for Bb
    37 specific for Bb
    38 cross-reactive for Bb
    39 is a major protein of Bb flagellin; specific for Bb
    41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
    45 cross-reactive for all Borellia (sometimes people with Lyme who have this band positive also have the co-infection Ehrlichiosis)
    50 cross-reactive for all Borrellia
    55 cross-reactive for all Borrellia
    57 cross-reactive for all Borrellia
    58 unknown but may be a heat-shock Bb protein
    60 cross reactive for all Borrellia
    66 cross-reactive for all Borrelia, common in all bacteria
    83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
    93 unknown, probably the same protein in band 83, just migrates differently
    in some patients

    The IgM tests for a more recent infection, the IgG a longer standing one. Bands 23-25, 31, 34, and 39 are Lyme specific bands. Band 41 is often the first to show. On your tests these bands are IND and positive.

    I agree with you that you need to see a Lyme doctor. If you need a recommendation, let us know okay?

     
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