First time poster after having tried numerous message boards, doctors, neurologists and treatments. Close to giving up.
Symptoms - Excruciating burning pain in buttocks;
- Excruciating burning pain in backs of thighs, extending down to calves and soles of feet.
Medications tried - Lyrica
- Amitriptyline
- Neurontin
Current medications
These last 2 medications are new, so I can't vouch for how well they will work at this point.
I've been dealing with this pain for around 7 years without relief. I rarely sleep, am unable to sit for longer than 5 minutes without the pain becoming unbearable and even lying flat on my back increases the burning pain to beyond my limits.
one doctor suggested that I may have Piriformis Syndrome (nerve compression by damaged piriformis muscle in buttocks) and after having done a ton of research on my own, it's the only condition that perfectly describes all my symptoms.
However, my doctors tell me that it's a rare condition and "highly unlikely". I already know that narcotics don't help with neuropathic pain and yet I have still been prescribed both Tramadol and Endone in the past which I have taken - after all, having tried everything else, I'll try anything - and no, neither of these narcotics help.
I'm beside myself with the never ending pain and don't know where else to turn to for help. I have an MRI scheduled for June (earliest I could get in) but don't know even if this will show anything new.
I found several exercises suggested to stretch the piriformis muscle, which I began last week, time will tell if these will help.
I'm considering pushing for a nerve block - any thoughts?
Possible Piriformis Syndrome 
