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desipramine for pain

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Old 03-17-2006, 02:34 PM   #1
Pebble Beach
Join Date: Feb 2005
Location: New Jersey
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Pebble Beach HB User
desipramine for pain

Hi all. I previously posted that I was on amitriptyline but was having trouble with it. I would sleep half the day away and then would feel like I was groggy and unable to function when I was awake.

So my pain management specialist put me on desipramine which i believe is an anti depressant but also used for chronic pain. I just started it about a week ago. I am Not drowsy from this medication but not sure it is doing a hole lot for the pain management.

Has any one been on this? Any good or bad results from it? Look forward to your opinions on the medication.

Thanks for listening.


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Old 03-17-2006, 03:25 PM   #2
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Join Date: Oct 2001
Location: Washington
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Re: desipramine for pain

Hey Allan: I don't really know a lot about this drug, so I did a look up and you're right, it's an antidepressant and mood elevator. The top of the list for side effects is dry mouth. Sorry I can't give you any personal information on it, but I take 50 mg of Amitriptyline at bedtime and haven't had any problems with it.

Old 03-17-2006, 04:38 PM   #3
Join Date: Aug 2005
Location: USA
Posts: 462
conductor HB User
Re: desipramine for pain

Dear Allan (Pebble Beach),

Desipramine and amitriptyline are both tricyclic antidepressants. I use 50 mg of amitriptyline each night, and I believe it has helped with the pain relief and my sleeping.

However, so many of these medications affect different people in different ways. I don't have any experience with this medication, either. So, I hope someone else who reads this board can help you!

Jon (Conductor)

Old 03-17-2006, 07:58 PM   #4
Join Date: Feb 2004
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shambbles HB User
Re: desipramine for pain

Hi Allan,
Im also on amitriptyline for nerve pain. Like you, I used to feel so out of on this medication but after a while most of the side effects go away or I've just got used to them. I've tried stopping the medicine but the pain just creeps back up so I won't be doing that again any time soon. It's also great for my sleep.

Best of luck to you.

Old 03-17-2006, 10:24 PM   #5
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Re: desipramine for pain

I was on that med. about three yrs ago. It didn't help all that much,but everyone is different. It takes about two weeks for it to work its way in your system.If i remember ,i was started on 50 mg. for three or four days,then up to a hundred.I took it for almost a yr.Another thing this med. is used for,is for bed wetting,anxiety,and pain.

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