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  • PCOS Uncontrolled by Metformin

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    Old 10-30-2009, 06:06 PM   #1
    SassyAtty's Avatar
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    Angry PCOS Uncontrolled by Metformin

    I'm just wondering if anyone else out there has had or is having a similar experience to my current state. I was diagnosed with PCOS almost 8 years ago when I was 23. I was prescribed Metformin, lost 60 lbs., had normal periods etc. etc. etc. Earlier this year, I started having trouble with my cycle again. I started having a period every other week and they were more painful than anything I've ever experienced. I was bleeding excessively and it was very....clotty. (Sorry for the visual!). I've gained almost 25 lbs, even while working out almost daily and being on the South Beach Diet (which is what I was on when I originally lost the 60 lbs without exercise). I'm exhausted; I could sleep 24/7. I was told by my PCP to increase my dosage of Metformin to 850 mg X 3 daily. I did, and it helped for a month, sort of. Instead of a period every other week, I had a "normal" cycle of 27 days. All other symptoms stayed the same. Since that one "normal" cycle, I'm back to every other week.

    I saw my PCP again yesterday to discuss the results of recent blood tests. He says that my hormones levels are severely out of whack. He has referred me to a specialist in Endocrinology and a specialist in high risk Gynocology. He said that my PCOS is not being controlled by the metformin and that currently my hormone levels are those of someone headed into menopause. At age 30.

    Beyond being shocked, this just doesn't make sense to me. I thought the major "sign" of heading into menopause was a lack of periods. That is definitely not my problem. I've tried doing research to determine a possible cause, but of course everything I read about PCOS and irregular periods discusses women who have long cycles, not enough periods. I have too many.

    Has anyone else had this experience? Has anyone else had perfectly controlled PCOS go crazy after years of metformin use? Does this sound like symptoms of something completely different?

    Any advice or insight would be greatly appreciated.


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    Old 11-02-2009, 08:28 PM   #2
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    Join Date: Sep 2006
    Location: Ozarks in Arkansas
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    Oleander53 HB UserOleander53 HB UserOleander53 HB User
    Re: PCOS Uncontrolled by Metformin

    You need to be seen by a Reproductive Endocrinologist who knows PCOS. If you live anywhere by Rhode Island I highly recommend Dr John Buster at Tufts.

    You may need Janumet which is 2000 of Metformin daily and some other medication called stiglipin sp? There are other things you can do....... Do not give up or be discouraged. Get to a good Doc that specializes in this.

    Good luck from an old PCOS lady........ Oleander

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