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Dopamine + Flip out = Psychosis

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Old 02-01-2013, 10:45 PM   #1
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Dopamine + Flip out = Psychosis

Hello Friends,

Following up my first Dopamine Flip out post, yeppers I done Flipped out for sure and in dramatic fashion. I started taking Mirapex a few weeks ago to combat RLS. I was started at a low dose (0.125mg/d) and it seemed to cut down on the severity of the RLS events -I wasn't jumping out of bed at 3am like I was on fire... My PCP okayed bumping the dose up to 0.250mg/d and that is when some strangeness began to take hold. Over several days my brain felt like it had a white noise machine blaring in the background, I was flooded with racing thoughts, my speech was disorganized, I couldn't arrange my thoughts, and I was completely flustered and unable to solve the most mundane problems. I also had trouble understanding what people were saying to me and even several emails with my Shrink I couldn't explain what was happening to me and had to tell him that I didn't understand a word he was writing in return. about 3-4 days ago I stopped the Mirapex completely and I seem to be coming back to this world, still a few brown outs here and there.... It is believed by my shrink that that Mirapex, being a Dopamine agonist working on D2 receptors threw me into Acute Psychosis. I was veering into mild symptoms of Schizophrenia. I'm a little embarrassed to tell my PCP about this because I pushed him to let me try it and he was 'hesitant' for that very reason, ouch! I may have the guts or stupididty to try it again to see 100% for sure if what happened can happen again so that I can squarely pin the blame on Dopamine activity. Do you guys think it would be a bad idea or dangerous for me to test the theory? I really want to know for certain.


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dopamine, psychosis

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