It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Schizophrenia Message Board

  • Schizophrenia and Autoimmune Disease

  • Post New Thread   Closed Thread
    Thread Tools Search this Thread
    Old 07-12-2006, 05:32 PM   #1
    kassy34
    Newbie
    (female)
     
    kassy34's Avatar
     
    Join Date: Jul 2006
    Posts: 5
    kassy34 HB User
    Schizophrenia and Autoimmune Disease

    --------------------------------------------------------------------------------

    American Journal of Psychiatry 163:521-528, March 2006
    doi: 10.1176/appi.ajp.163.3.521
    © 2006 American Psychiatric Association
    This Article








    Articles by Eaton, W. W.
    Articles by Mortensen, P. B.

    PubMed

    PubMed Citation
    Articles by Eaton, W. W.
    Articles by Mortensen, P. B.

    Related Collections

    Schizophrenia Spectrum Disorders

    Atypical Neuroleptics

    Genetics
    Related Article



    Association of Schizophrenia and Autoimmune Diseases: Linkage of Danish National Registers
    William W. Eaton, Ph.D., Majella Byrne, Ph.D., Henrik Ewald, Dr.Med.Sc., Ole Mors, Ph.D., Chuan-Yu Chen, Ph.D., Esben Agerbo, M.S. and Preben Bo Mortensen, M.D., Dr.Med.Sc.
    OBJECTIVE: Individuals with schizophrenia and their relatives tend to have either higher or lower than expected prevalences of autoimmune disorders, especially rheumatoid arthritis, celiac disease, autoimmune thyroid diseases, and type 1 diabetes. The purpose of the study was to estimate the association of schizophrenia with these disorders as well as a range of other autoimmune diseases in a single large epidemiologic study. METHOD: The Danish Psychiatric Register, the National Patient Register, and a register with socioeconomic information were linked to form a data file that included all 7,704 persons in Denmark diagnosed with schizophrenia from 1981 to 1998 and their parents along with a sample of matched comparison subjects and their parents. The data linkage required that the autoimmune disease occur before the diagnosis of schizophrenia. RESULTS: A history of any autoimmune disease was associated with a 45% increase in risk for schizophrenia. Nine autoimmune disorders had higher prevalence rates among patients with schizophrenia than among comparison subjects (crude incidence rate ratios ranging from 1.9 to 12.5), and 12 autoimmune diseases had higher prevalence rates among parents of schizophrenia patients than among parents of comparison subjects (adjusted incidence rate ratios ranging from 1.3 to 3.8). Thyrotoxicosis, celiac disease, acquired hemolytic anemia, interstitial cystitis, and Sjögren’s syndrome had higher prevalence rates among patients with schizophrenia than among comparison subjects and also among family members of schizophrenia patients than among family members of comparison subjects. CONCLUSIONS: Schizophrenia is associated with a larger range of autoimmune diseases than heretofore suspected. Future research on comorbidity has the potential to advance understanding of pathogenesis of both psychiatric and autoimmune disorders.

    assy

    Last edited by kassy34; 08-15-2006 at 07:15 PM.

     
    Sponsors Lightbulb
       
    Old 07-13-2006, 07:18 PM   #2
    Fierysungirl
    Junior Member
    (female)
     
    Fierysungirl's Avatar
     
    Join Date: Jun 2006
    Location: Harrisonburg, Va
    Posts: 22
    Fierysungirl HB User
    Re: Schizophrenia and Autoimmune Disease

    My theory on autoimmune diseases (I AM NOT A DOCTOR OR MEDICAL PROFESSIONAL--I AM JUST A SOCIAL WORKER WHO HAS SEEN PEOPLE WITH AUTOIMMUNE DISEASES AND HAS SOME IDEAS ABOUT IT)

    is that they must have a psychosomatic origin. With autoimmune diseases, your immune system and other bodily defense systems are in overdrive and instead of attacking bad things in your body, they attack they body itself.

    So, basically, your body is attacking itself. I think people with low self esteem or repressed anger or hatred towards themselves develop theses diseases because they don't like themselves, thus their own body attacks them.

    This could also happen to people who seem happy, but push themselves too hard and can't accept themselves unless they are loved and perfect at what they do, which could be why seemingly happy people like Michael J Fox and Montel Williams got these types of diseases.

    Basically, if you don't like your body or show your body respect by getting rest your body could start to attack itself.

    Back to schizophrenia or even other mental illnesses, the stress and stigma of having this ilness could cause one to develop an autoimune disease.

    Just my opinion.

     
    Old 07-23-2006, 10:23 PM   #3
    Shayone478
    Junior Member
    (female)
     
    Shayone478's Avatar
     
    Join Date: Jun 2006
    Posts: 14
    Shayone478 HB User
    Re: Schizophrenia and Autoimmune Disease

    Quote:
    Originally Posted by kassy34
    Hi I'm new to this board and I'm wondering if any family's with schizophrenia history also have autoimmune disease.
    My sister is schizofrenic and also has some autoimmune diseases . Other members of my family including myself have differant autoimmune diseases.

    I'm leaving an interesting study to new research into this link and would like to hear from others that have these same issiues.

    Thanks Kassy
    --------------------------------------------------------------------------------
    American Journal of Psychiatry 163:521-528, March 2006
    doi: 10.1176/appi.ajp.163.3.521
    © 2006 American Psychiatric Association
    This Article Articles by Eaton, W. W. Articles by Mortensen, P. B.
    PubMed PubMed Citation Articles by Eaton, W. W. Articles by Mortensen, P. B.
    Related Collections Schizophrenia Spectrum Disorders Atypical Neuroleptics
    Genetics Related Article
    Association of Schizophrenia and Autoimmune Diseases: Linkage of Danish National Registers
    William W. Eaton, Ph.D., Majella Byrne, Ph.D., Henrik Ewald, Dr.Med.Sc., Ole Mors, Ph.D., Chuan-Yu Chen, Ph.D., Esben Agerbo, M.S. and Preben Bo Mortensen, M.D., Dr.Med.Sc.

    OBJECTIVE: Individuals with schizophrenia and their relatives tend to have either higher or lower than expected prevalences of autoimmune disorders, especially rheumatoid arthritis, celiac disease, autoimmune thyroid diseases, and type 1 diabetes. The purpose of the study was to estimate the association of schizophrenia with these disorders as well as a range of other autoimmune diseases in a single large epidemiologic study. METHOD: The Danish Psychiatric Register, the National Patient Register, and a register with socioeconomic information were linked to form a data file that included all 7,704 persons in Denmark diagnosed with schizophrenia from 1981 to 1998 and their parents along with a sample of matched comparison subjects and their parents. The data linkage required that the autoimmune disease occur before the diagnosis of schizophrenia. RESULTS: A history of any autoimmune disease was associated with a 45% increase in risk for schizophrenia. Nine autoimmune disorders had higher prevalence rates among patients with schizophrenia than among comparison subjects (crude incidence rate ratios ranging from 1.9 to 12.5), and 12 autoimmune diseases had higher prevalence rates among parents of schizophrenia patients than among parents of comparison subjects (adjusted incidence rate ratios ranging from 1.3 to 3.8). Thyrotoxicosis, celiac disease, acquired hemolytic anemia, interstitial cystitis, and Sjögren’s syndrome had higher prevalence rates among patients with schizophrenia than among comparison subjects and also among family members of schizophrenia patients than among family members of comparison subjects. CONCLUSIONS: Schizophrenia is associated with a larger range of autoimmune diseases than heretofore suspected. Future research on comorbidity has the potential to advance understanding of pathogenesis of both psychiatric and autoimmune disorders.

    assy
    I just have a comment regarding studies such as this. I am a little cynical when it comes to the world of medicine so please do not take my comment personally Kassy. But why the heck do these doctors have to waste their time and the ppls money on these studies? I do not get where they are actually going to help any people with this 'proven' knowledge. I mean it's only common sense that the 2 would be linked if you think about it. Will the science communities ever learn or recognize that in order to treat part of a being you have to consider it as a whole? What I mean by this is that you need to treat the body and mind, since they are really one whole. You can't fix one without fixing the other, as one can't be broke without the other also being broke. I just wish this would be more widely accepted and implemented. Instead of scientists trudging further on down a path that is not getting our societies anywhere healthier. The way I see it is they're just keeping their pockets lined.

    What is 'advancing the understanding of the pathogenesis of psychiatric and autoimmune disorders' going to lead to?

    That's just my 2 cents.

     
    Closed Thread

    Related Topics
    Thread Thread Starter Board Replies Last Post
    macrocytic anemia and low platelets flemmy Anemia 2 11-24-2009 01:15 AM
    Lymph Nodes and Autoimmune Disease? Mr. Strangeheart Immune Disorders 25 07-29-2008 11:11 AM
    drug induced psychosis or schizophrenia? frankiefloris Schizophrenia 21 02-21-2008 04:43 AM
    autoimmune enteropathy? salamandertom Immune Disorders 7 01-29-2008 07:10 AM
    family with a lot of autoimmune diseases trouble222 Immune Disorders 2 06-20-2007 09:30 AM
    Schizophrenia and Me craazy Schizophrenia 1 08-10-2005 01:19 AM
    I tested positive for an autoimmune disorder coryb Inner Ear Disorders 8 09-27-2004 06:15 PM
    Diagnosing Schizophrenia - How long does it take? achtung Family & Friends of the Mentally Ill 3 07-21-2004 07:07 AM
    Can schizophrenia or the medication you take for it suppress the immune system? zoron Schizophrenia 11 05-19-2004 10:11 PM




    Thread Tools Search this Thread
    Search this Thread:

    Advanced Search

    Posting Rules
    You may not post new threads
    You may not post replies
    You may not post attachments
    You may not edit your posts

    BB code is On
    Smilies are On
    [IMG] code is Off
    HTML code is Off
    Trackbacks are Off
    Pingbacks are Off
    Refbacks are Off




    Sign Up Today!

    Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

    I want my free account

    All times are GMT -7. The time now is 10:25 PM.





    © 2021 MH Sub I, LLC dba Internet Brands. All rights reserved.
    Do not copy or redistribute in any form!