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    Old 07-01-2004, 08:29 PM   #76
    ronaldo1
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    Re: new dry eye discussion

    Hi Elyse,

    Your theories on why you get pink eye all the time seem very logical to me. The dryness keeps the bad bugs and bacteria on your eyes, where they breed and multiply. On occassions when I have taken the kids to the doctor for pink eye, they have suggested that it can be caused by shampoos and other irritants entering their eyes during bath time etc. My son is also going through a phase of touching the bottom of his shoes (yuk) and then he is tired, rubbing his eyes, which I suspect is the cause. Now I do not believe that any of these reasons would be the cause of your problems, so the dryness connections seems like a reasonable one. Obviously infections are linked to immunity. When you get tired and run down and your immunity is not at its peak, you are also more prone to infections. I read your posts on the MS board and suspect that the fact that you experience extreme tiredness and lowered immunity levels may also be contributing to this. What do you think?I am no doctor, so it is only my opinion... am probably totally off the planet. Anyway, I hope that you have found some relief since your last post.

    I am seeing my eye doctor on wednesday and will ask him about the new eye drops and whether he is going to be involved in the clinical trial out here. He did mention that they were testing some other cream but I do not recall the name.

    I do not understand the whole acid /stomach thing. I think the endoscopy confirmed that the excess acid has not caused damage to the lining of my stomach/ throat and that it is not being caused by a loose sphincter muscle, but it did not reveal why my stomach is making so much excess. I think that I have a very poor digestive system , with very little nutrients being absorbed which is why I am always so tired and maybe my stomach is over compensating for the sluggishness by making too much acid. Anyway, the tablets I am on are helping on this front, but I am determined to keep seeking answers about why this is happening.

    Anyway, take care
    Christine

     
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    Old 07-02-2004, 09:17 PM   #77
    znawfal
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    Re: new dry eye discussion

    Hi everyone,

    I have been following this forum for a while now (maybe a year or so)... i am not a frequent poster but i have a question for those who use doxycycline. I am a meibomitis sufferer (or rosacea sufferer, depending on the dr diagnosis) ;(

    My dr. started me with periostat (doxycycline 20mg tablets) with no improvement. Now he prescribed to me 50mg twice a day... Now the pharmacist told me that there are several types of doxycycline delivery that would affect the way the body receives them... He mentioned "hyclates" also maybe "tablets vs. capsules".

    For those using doxycyclines, can you please please tell me what is the brand name u aare using and more importantly whether it is a capsule or a tablet ...

    I am optimistic about the doxycyline new dosage.

    I am planing to try Restasis with the doxy if doxy does not work alone..

    He also mentioned that he thinks that the plugs could be causing the redness to increase ... so he removed the upper ones ... and he even suggested removing the lower ones,,, which is something i refused to do (at least for the time being) ...

    Did anyone suffer from such increased redness from the punctum plugs.

    MANY THANKS

     
    Old 07-15-2004, 10:02 PM   #78
    ronaldo1
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    Re: new dry eye discussion

    Hi Elyse,

    How are the problems with the pink eye? Has it gone away, or are you still having problems? I hope it has settled down and that you have had some relief.

    I saw my eye doctor two weeks ago. It was time for a repeat schirmers test, so that he could justify to the government here that I have shown some improvement with the restasis. He did not seemed thrilled, but I was pretty happy when he told me that after 5 minutes, my tears wet the paper 5mm on the left eye and 4mm on the right eye. So, I guess that is better than my big fat ZEROmm schirmer results when I first saw him in 2002. the strange thing was the fact that my left eye, which has always been more problematic than the right actually scored the highest....I cannot figure that out. Anyway, he asked me whether I am happy to continue using it and I told him that I would never not consider using it. He is also hoping to get involved in the clinical trials for the new drops. I feel very lucky to have him as my doctor, as some others that I saw did not have a clue what was going on.

    Have you been back to your eye doctor lately?

    Would love to hear how you are going
    Christine

     
    Old 07-15-2004, 10:55 PM   #79
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    dry eye after cataract surgery

    I have had a dry eye(feels like sand in it) since my cataract surgery. My Dr. tells me everything has healed well and it is probably from the Prednisolone drops that I had to put in after. Told me just to use artificial tears and eventually it will be OK but I wonder if it ever will be. It has been 7 weeks since surgery. I have no crusting or anything though. Just this sand feeling when I blink my eyes. Anyone had this?

     
    Old 07-16-2004, 10:57 PM   #80
    ronaldo1
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    Re: new dry eye discussion

    Sorry to hear about the problems you have been having since your surgery. I am certainly no expert, but in the case of dry eye sufferers my experience has been that steroid drops actually help with the dryness, by reducing the inflammation in the eyes/eyelids, as opposed to causing the problem as your doctor suggests. Also, artificial tears only provide relief for dry eye sufferers but will not address any underlying problem causing the dryness in the first place.

    A schirmer test would certainly be able to diagnose any other problems that you may be having with dry eyes. This is when they put two strips of paper in your eyes to measure the amount of tears your eyes make after 5 minutes. If your eye doctor is not willing to do this test, then I would suggest seeing someone else for a second opinion. I know that sometimes, surgery such as lasik can result in dry eyes, but I do not know much about cataract surgery.

    I hope that I was of some help. I wish you the best of luck.
    Christine

     
    Old 07-18-2004, 11:32 PM   #81
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    Re: new dry eye discussion

    thanks, Christine. Actually the Dr. told me that the steroid drops tend to dry the eye and he had me switch to Prednisolone Forte which is non generic. Anyway, I decided to go off all drops and have had no problem since then. I think my regular tears are working OK now because within 12 hours after I stopped all drops the problem went away. Hope it stays away. I had to take the steroid to keep down the inflammation after surgery but haven't had to take them for awhile. Was just using Tear Naturelle. I am sure he would do test if it continued. Anyway, thanks

     
    Old 07-22-2004, 12:34 AM   #82
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    Re: new dry eye discussion

    Hi guys,

    Sorry I haven't replied in a while. I was having computer problems, but they seem to be under control at the moment! I just didn't want to go on the internet until I got my Norton Internet Security installed.

    Christine, I am so glad to hear that you had an increase in tear production on your last schirmer test. It's about time for some good news! I think it's so ridiculous that the govenrment is still regulating Restasis so much though! I am glad it seems to be helping you though, even if it is taking so long. I can't wait until the Diquafosol drops become available. I need something to work for me!

    I went back to the eye dr today, and he was not too pleased. Apparently I have more than enough of the watery layer of tears, but even with the Doxycycline and hot compresses I have NO oil or mucus in my tears. For the past few days I have been getting a lot of tears running down my cheeks. Optimistically, I thought that maybe that was just because I had "too many tears". (as if it is possible!) But if that were the case my eyes would not be burning unbearably like they have been. My doctor said that I basically ONLY have water in my tears, and so they are not sticking to my eyeballs. What good is the watery layer without the mucus and oil layers?

    He was really disappointed because we both had hoped that by now something would have started working. But the surfaces of both eyes look really bad.

    Earlier you were all speaking about the different types of Doxycycline. The one I am taking has no special name. It is just called Doxycycline. It is a blue and white 50 mg capsule. I am taking 150 mg, so I take 3 capsules a day. My doctor started me out on a very low dose. The usual dose is something like 300 mg a day, but I have such a sensitive stomach that he was worried that the doxycycline might aggravate things. So he is increasing it very very gradually until we reach the desired dosage.

    I found out about a new product. Well, it's not really new (been around for about a year) but it's the first that I've heard of it. It's called Nature's Tears Mist. It's simply made from Tissue-Culture Grade Water. It's not a drop, but a mist that you spray in your eyes. It's good for when I'm driving and can't stop to put drops in. It's available at most pharmacies, but it can also be purchased directly from the company on their website. Just look up Nature's Tears, and you'll find it. It doesn't help all that much, but it just makes my eyes bearable until I can get the tear drops into them. I brought it to my doctor today to show him, and he was so curious that he tried it on his own eyes! He said that it made his eyes feel slightly "smoother". That's a good way to describe it. We also conducted a little experiment. He examined my eyes and saw how awful they looked. Then I sprayed this stuff in them, and he examined them again to see if there was any change. There was not, but at least I didn't have a bad reaction to it! It does make my eyes feel slightly better, so I am going to keep it in the car and use it when I am driving.

    The only good news that I got today is that I have no current infection. Maybe the hot compresses are finally starting to help.

    Speaking of which, I better go use another one!

    Hope everyone is OK,
    Elyse

     
    Old 08-01-2004, 10:23 PM   #83
    ronaldo1
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    Re: new dry eye discussion

    Hi Elyse,

    Well I am glad thatthings have finally settled down for you with the infections. Keep up the good work with the hot compresses. It must be making a difference by cleaning out some of the gunk that loves to accumulate on our eye area!!

    I spoke too soon about my eyes. Ever since I saw my eye doctor three weeks ago, I have gone back to having the same problems with my left eye that I had before I started using Restasis. My left eye has been very dry, irritated and feels like there is something constantly in it, so it is always on my mind. I examined my left eye and saw that the oil gland on the top lid, which has always been a problem for me, was blocked up again, and also, in the pink part of my eye in the lower lid area, I also have a small limp which resembles a blocked oil gland. It constantly rubs against my eye and is really annoying. It has been this way for about 3 weeks and the restasis does not seem to be making any impact. I am feeling a little depressed about this as I thought that I was one of the lucky ones that was able to tolerate restasis etc, however my eye is as bad as it was before. Does anyone know whether there are oil glands in the pink part of the eye in the lower lid? I am about to start doing the warm compresses again...hope it works.

    I cannot wait for the new drops to come out as well. Fingers crossed that it helps all of us.
    Christine

     
    Old 08-02-2004, 11:34 AM   #84
    ajneedhams
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    Re: new dry eye discussion

    Hi Christine- I'm sort of new to this board. I've had dry eyes for three months. My story is on here somewhere under the thread "Dry Eye...Help." Anyway, I was curious about your case because I also have used the Restasis. I know how hard it was for you to try and get approval/authorization for it. It seemed to work for me early on like week 2 or 3, but I ended up discontinuing at 6 wks. It started to burn my eyes and that lasted for a long while. My eyes slowly started feeling dryer as well. The Doxy hurts my stomach at night. I've been very depressed over this matter. All of this came on quite suddenly after my initial pink eye episode in which I was treated with antibiotics in both eyes. I never had a detectable problem and wore contacts happily and successfully for 20 yrs. I am a 35 yr old who is now waking and thinking about my eyes far more than I should or ever wanted to. Have you had plugs? Just curious about what else you have tried?? Sorry to hear the Restasis wasn't the complete answer to your prayers. It is hard to be there for your kids when you worry about your eyes all the time. I have a 4 and a 6 yr old.

    Amy

     
    Old 08-03-2004, 05:59 AM   #85
    ronaldo1
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    Re: new dry eye discussion

    Hi Amy,

    Welcome to the board. I am glad that you replied as our circumstances seem to be very similar. I am also 35 years old and my children and 3 and 1/2 and 6 and 1/2. I have had dry eyes since April 2002 and as in your case, my dry eye problem seemed to appear overnight and blew me away when it happened I had no idea what was going on at first).

    Well, you asked what I have tried, so here it goes. First I was on minomycin oral antibiotics which did very little to help. Then, I was on a tetracycline antibiotic also which helped very little. When I saw my current eye specialist, he put me on doxycycline 100mg which actually resulted in some improvement in the dryness, however some days it would be ok and other days it would still be awful and I could never understand why it differred from day to day. Anyway, my doctor eventually got government approval to import Restasis to Australia from the US and I have been using it since November 2003. It has helped me more than anything else, although lately my left eye has been playing up again, for some unknown reason. I do get burning sensations with the restasis but it seems to come and go throughout the day, so while iut is painful and annoying, I just manage to cope with that. My eye doctor did give me some FML drops to use when the burning gets too bad, but so far, I have not tried it. I understand that this can cause an increase in eye pressureand I figure I have enough problems already.

    I stopped using the doxy once I started using Restasis as I had been on antibiotics for 15 months and I figured that it was not doing my body any favours.

    I have also tried a large number of antibiotic drops like Bleph 10, to control the blepharitis, which in my casue caused an allergic reaction.

    I have not tried plugs, as my doctor told me that in my case, they would probably make matters worse as the bacteria which normally gets washed away by the tears produced by someone with normal eyes, would "hang around" in my case, as I do not have enough tears to wash them away. Hence the bacteria would multiply on my eyelids and make the blepharitis even worse...!

    Before I started using restasis, I was also thinking about my eyes every minute of every day. I felt like tugging off my eyelids at times and I was just so miserable. Now, I do get some relief at times, when my eyes are not burning and when my oil glands are not too blocked.

    Have your doctors worked out why your eyes are dry? I have meibomian oil gland dysfunction. If this is the cause of your dryness, putting warm compresses on your eyes several times a day can help unblock the oil glands. I also clean my eyelids with diluted baby shampoo to keep the blepharitis at bay.

    I can truely understand how you feel, as I have been going through this for over two years now, and at times it can be really hard to stay positive. But you have to hang in there, use lots of artificial tears and try the warm compresses. My doctor tells me that new drops are in the process of being developed and tested and should be available in the US by 2006 ( I wish I lived there!), so all we can really do is hope that it will be the answer for all of us.

    Did your doctor suggest discontinuing the restasis? I am just curious, because my doctor told me that I would not realise the full benefit of the restasis until I used it for 3 months as it has a cumulative effect over time. In my case, it did help, as my schirmer tests have improved (previous I scored ZERO tears after 5 minutes and now I am up to 4mm) and he also said that the level of abnormality on the eye surface had decreased. I can really vouch for 3 months as being the turning point for me. After 6 montsh however, the effect has reached a plateau and I am not sure what further benefits I may get form this point on. Was the burning sensation in your eyes constant, or did it come and go throughout the day? If it did come and go, perhaps it is worth perservering with the restasis until the 3 month mark to see whether you do see an improvement...only a suggestion????

    hang in there!
    Christine

     
    Old 08-03-2004, 04:25 PM   #86
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    Re: new dry eye discussion

    Thanks Christine! I am hanging in here, but it's tough. I just want to be normal again. My family is getting ready for a camp trip this Thurs and this will be the first time I've gone in the midst of dealing with all this dry eye crap. I have to make sure to bring my little tears vials and ointment. I don't want to find my eye stuck to my lid in an unfamiliar tent.

    I was awestruck to hear that you are my same age and have two little ones. I have a girl and a boy. They have been pretty oblivious to all of my discomfort, but they do notice that Mom cries a lot more and feels blue. That in itself makes me sad. We take our eyes for granted.

    You said your symptoms came on overnight. Was there a particular thing that coincided.........an infection, or new contacts, allergy, anything?....etc)
    The first opth I saw said that I might possibly have bleph, but it seems strange that it would be so sudden. He said I probably always had it, but that it only just started to become symptomatic. I'm not sure I buy it. (in my case, that is) Nobody has really been able to pinpoint where my problem lies. Is it Meiobian (MDG) or lacrimal? My Schrimer's was pretty low. Something like 4mm and 5mm. Not sure what it was before I actually began Restasis. I have mixed feelings about having stopped it. I was having an exceptionally bad day when I threw in the towel. I am seeing a new opth Thurs and will get his opinion. Have you heard of a tear test which is actually a tear analysis that tells you what your tears are composed of? I forget what it is called. Micro assay tear testing or something>?? I think that would be helpful. Not sure if my Dr's office has it. I cancelled an appt for tomorrow for plugs with the same Dr. I wanted to get a "3rd opinion." One thing about me, I am sort of neurotic when it comes to my health. I want to make sure I'm doing the very best that I can for myself and not do anything too drastic. I don't like to take drugs/meds as a rule either. The constant Doxy and Restasis made me uncomfortable with the amounts of drugs I was instilling every day. By the way, how long did it take for you to find some relief with the Doxy?? Was it months as they say?? It seemed to irritate my stomach at night and is it possible to make your mouth dry too?? I thought that was a side effect that I was having. Then I get concerned that maybe I have Sjrogens and I get anxiety about that too. A rheumatologist thinks he ruled that out, but in the back of my head, I'm still wondering.... Gosh, I wish there were some others nicer, fun things to fill my head with in the wee hours of the night.

    My husband and me (along with our son and daughter) have always been active, enjoy the outdoors etc, and dealing with this has been almost crippling. Do you use an ointment during the night? Any advice for a good one? Also, since you have such poor Schrimer's wetting, obviously you have lacrimal deficiency as well......am I correct? Can you cry okay?? My tears feel good, but they dry so fast. Sometimes I cry just for the sake of tears. And, I'm always self inducing yawning, because the slightest wettness feels good. If you have MGD caused by bleph, do you have visible particles in your lash line? How does one know that their meiobian glands are blocked? I see nothing visible. When I pull down my lower lid, I can see some slight liquid that looks oily that pools in the bottom. How would I know if I had a blockage? It is so confusing. For me, the nighttime is the worst. I dry out exceptionally bad and my eyes are often crusty in the AM. Much better after a shower. Most days I just deal with a moderately dry feeling and some burning. I dread night though. What artificial tears do you use/recommend?

    Well, I know that I've asked you a lot of questions. I'm lucky if you can respond to any of them. Truely appreciated.

    Amy

     
    Old 08-03-2004, 11:31 PM   #87
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    Re: new dry eye discussion

    Hey everybpdy! Sorry I haven't been here in a few days. I have got 8 midcro-abrasions on the cornea of my left eye. Appaerently my eye got so dry (the left one is always drier than the right.) that just blinking caused these tiny abrasions. I was on Vigamox anti-biotic drops for a week, as well as FML steroid ointment once a day because the surface of the eye was so inflamed. I went back today and unfortunately my eye has not gotten much better. I still have the abrasions and even though they have healed slightly, the surface of the eye is even more inflamed than it was before. My doctor thinks that while the Vigamox is a great anti-biotic, my eye is so irritated that such a strong medicine inflamed the surface even more. He thinks it was too strong for me in this particular case. So he took me off of that and put me on one that is slightly weaker so I won't be irritated. In addition, since the surface is soooo inflamed, I need to use the steroid ointment 3 times a day, much to our dismay. (we know that eventually, steroids will make my pressure go up and we wanted to stay away from them.)

    I am feeling better since I stopped the Vigamox though. The steroid ointment is helping too. I go back in a week for another follow-up, unless of course I feel worse before then.

    So in addition to the prescribed medicine, I am using tears about 15 times a day because my eyes are sooooooo dry. I seem to go through these periods evey few months or so when they just get worse. Then they sort of maintain themselves for a little while, maybe get slightly better, and then get worse again. It's a vicious cycle. The hot compresses don't really seem to be working, but they do at least make my eyelids feel less itchy and crusty.

    Amy, the only way that you'd be able to tell for sure if you have clogged meibomian glands is for an ophthalmologist to examine you and look at them. Also, sometimes my eyelids stick together and some people say that they can see oil coming out of their clogged glands, especially after they use a hot compress. Good luck with the new ophthalmologist! I hope he is able to help you!

    I totally understand your confusion about why you were sentenced to have dry eyes. Mine came on pretty much overnight too. After I stopped wearing my contact lenses (which I tried for two weeks but they kept falling out) my eyes felt fine. But then one day a few months later (coincidentally, right after 9/11) I started having these problems. And they haven't let up since. Nobody can really tell me why I have dry eyes. We know I have meibomian gland dysfunction, but why do I have that? In my case, the theories include allergies and auto-immune disease (sjogrens). My neurologist says that my Multiple Sclerosis can't cause dry eyes, but I think that anything is possible. I mean, why haven't any of the treatments worked? God knows I've tried them all. I think that if MS can cause nerve damage, why can't it cause damage to the nerves that make the eye produce tears? It's a long shot to say that it would cause damage to the nerves that tell the eye to produce the oily layer of tears, but I wonder if it's possible.

    After almost 3 years, I feel like I'm never going to find a cure. I'm not even looking for a cure anymore. I just want a suitable treatment.

    Last edited by purple2067; 08-03-2004 at 11:33 PM.

     
    Old 08-14-2004, 01:05 AM   #88
    ronaldo1
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    Re: new dry eye discussion

    Well guys you are not alone! I have been suffering a lot of dryness with my left eye in particular ever since I last saw my doctor in July. I was doing OK on the restasis and then for no reason my left eye decided to play its old tricks. I have even gone back onto the doxy in conjuction with the Restasis but it has only brought very minimal relief.

    My problem is definately oil gland dysfuntion, as the ey doctor was able to see tiny blockages on my eyelids, when he examined them. The one on my upper left lid is actually not so small and I can see it when it is inflamed and rubs against my eye. I hate it!

    Like most other people, my problem seemed to start overnight. The only thing it co-oncided with was my return to work after 12 months of maternity leave. I do not believe that I suffer from my eye related allergies, or other infections as the casue. My eye doctor once told me that it was due to "my male hormone receptors not working properly" whatever that means and when I pressed him about this, he was very vague. Apparently male hormones play some part in all of this.

    As negative as it sounds, I have given up hope of a cure. My eye doctor says that it can be managed, however he will not be able to return me to 100% normal (unfortunately). I use Polyvisc ointment at night and Visco tears duirng the day after I developed an allergy to using Genteal gel.

    I thought I had sjogrens as well and after having part of my inner cheek cut out, was told I do not. However, it is a very slow developing disease and it may be that a diagnosis does not happen until some years down the track. I even tried a course of strong steroids to try and reverse any possible effects of sjogrens but after several weeks my eyes were no better, so the doctor sort of ruled that out.

    Anyway, I am just plodding along along each day, hoping for relief and counting the days down until the new cream becomes available. Hang in there guys!
    Christine

     
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