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A question, if I may

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Old 12-09-2004, 03:04 PM   #1
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Maryee HB User
Smile A question, if I may

Hello all

I would be most grateful if you could help me in deciphering the results that I have had so far. By way of a brief background, having read the Thyroid thread, I think that I have been hyper for some 5-6 years and then went onto a period of hypo during the last 4 years, I went from one extreme to the other almost overnight, with the exception that I still have episosdes of flushing red hot face, hands, feet, knees (with swelling). I always just thought that I was hyperactive and had lots of energy, I got more done in a day than most people and was a high achiever, then I changed and became someone who feels yueky with no energy, tired, aching muscles with no strength and I sometimes get chest pains - you all now the drill! ;-).

My latest symptom (which actually promoted my doctor into doing something) is multinodular goiter, which is continuing to grow. The results of the tests that I have had so far are : TSH 8.32 (0.5 - 2.5), T4 of 14 (Dr didn't give me the range for this), she said that my peroxidase antibody level is 331 (normal = under 75), T4 borderline low of 12.5 and T3 normal of 5.3 (3.9 - 6.8). My Dr says that I am borderline hypo and probably Hasimoto's. She says that I have a normal thyroid but that my pituitary gland is producing an excess of TSH in order for this to happen.

I have an appointment with a specialist at the Hospital (my appointment doesn't say what sort though!) and I have been asked to bring along a urine sample (no fasting required). Could anyone be so kind as to explain to me what the urine sample will tell and I don't understand the bit about the pituitary gland producing excess TSH bit either?!

Thanking you in advance


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Old 12-09-2004, 04:37 PM   #2
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Meep HB UserMeep HB UserMeep HB User
Re: A question, if I may

Originally Posted by Maryee
Could anyone be so kind as to explain to me what the urine sample will tell and I don't understand the bit about the pituitary gland producing excess TSH bit either?!
The Urine might be for a Cortisol level, but there's no way to know without asking.

A little lesson in thyroid levels and how they are regulated in your body:

1. Your thyroid gland makes thyroid hormone and releases them into your blood for use.
2. Your Hypothalamus measures how much T3 and T4 is in your blood, and releases a corresponding amount of TRH.
3. Your Pituitary gland "measures how much TRH is in your blood and releases a corresponding amount of TSH.
4. Your thyroid gland releases tyhyroid hormones into the blood based on how much TSH it "measures"
5. Go back to number 2.

As you can see it is an indirect process. An elevated TSH indicates that your body (as indicated by yout hypothalamus and pituitary) is crying out for more thyroid hormone and your thyroid gland is not able to keep up with the demand. I disagree with your doc about your thyroid being "normal" as the TSH tells us it isn't.

The T4 being "borderline low" is the reason for much of your symptoms. Your T3 is in the middle of the range and is the most "normal" test you posted, but many people do better if it is a bit higher, still.

I am not a doctor, nor have I ever played one on TV...

Old 12-10-2004, 02:53 AM   #3
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Maryee HB User
Thumbs up Re: A question, if I may

Thank you Meep

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