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-   -   Low Free T4, High free T3, normal TSH (https://www.healthboards.com/boards/thyroid-disorders/656655-low-free-t4-high-free-t3-normal-tsh.html)

linabella 12-15-2008 08:31 PM

Low Free T4, High free T3, normal TSH
 
I was diagnosed hypothyroid in my 30s (I'm 53 now) and I've been on some medication (ether levothyroxine, synthroid, or Armour) for it most of that time.

I started experiencing debilitating fatigue in 2003. I switched from levothyroxine to Armour over a year ago. I have gone through three docs, trying to find someone who'll help me figure out why I'm so danged tired. I'm not depressed, except when I think I have to be tired for the rest of my life.

In July 07 my TSH was 1.96 and my Free T3 was 2.5
In November 07 my TSH was .63
In February 08 my TSH was 4.61
In September 08 my TSH was 1.65

I have rarely been able to get anything monitored other than my TSH without pitching a fit, but I did talk my doc's assistant into testing my TSH, Free T4 and Free T3 recently (December 08).

my TSH is .440 normal = .3 - 3.0
Free T4 is .59 normal = .7 - 2.0
Free T3 is 4.75 normal = 2.3 - 4.2

I'm really tired and now my muscles have started to get inflamed at night - achy like I have a fever, but no fever

Doctors keep suggesting antidepressants. I think my labs are odd.

Any ideas?
thanks!

midwest1 12-15-2008 09:43 PM

Re: Low Free T4, High free T3, normal TSH
 
[quote]Free T4 is .59 normal = .7 - 2.0
Free T3 is 4.75 normal = 2.3 - 4.2[/quote]
These are not normal. The FT4 is below range and the FT3 is above. You're right that they're "odd", and I'm not quite sure what to make of it.

What dose Armour are you taking? You may need to reduce it slightly and add some levothyroxine in order to boost the FT4.

linabella 12-15-2008 09:50 PM

Re: Low Free T4, High free T3, normal TSH
 
I'm taking 90mg armour thyroid

Oleander53 12-16-2008 09:25 PM

Re: Low Free T4, High free T3, normal TSH
 
Have you been tested for antibodies......

My t4 drops easily........ I am on 4 Grains of Armour and my Doctor ordered Cytomel in the afternoons to add to it.

I found I did better ( my t4 ) when I was on Thyrolar2 but I was taken off of it due to a milk allergy and it has a lactose base. I went back to Armour reluctantly....I have been on Armour over 2 years now.

My Endo says it is my Hashi's that makes my T4 drop just his opinion. My antibodies are negative.

o

hypoT 12-17-2008 03:28 PM

Re: Low Free T4, High free T3, normal TSH
 
[QUOTE=linabella;3822966]I was diagnosed hypothyroid in my 30s (I'm 53 now) and I've been on some medication (ether levothyroxine, synthroid, or Armour) for it most of that time.

I started experiencing debilitating fatigue in 2003. I switched from levothyroxine to Armour over a year ago. I have gone through three docs, trying to find someone who'll help me figure out why I'm so danged tired. I'm not depressed, except when I think I have to be tired for the rest of my life.

In July 07 my TSH was 1.96 and my Free T3 was 2.5
In November 07 my TSH was .63
In February 08 my TSH was 4.61
In September 08 my TSH was 1.65

I have rarely been able to get anything monitored other than my TSH without pitching a fit, but I did talk my doc's assistant into testing my TSH, Free T4 and Free T3 recently (December 08).

my TSH is .440 normal = .3 - 3.0
Free T4 is .59 normal = .7 - 2.0
Free T3 is 4.75 normal = 2.3 - 4.2

I'm really tired and now my muscles have started to get inflamed at night - achy like I have a fever, but no fever

Doctors keep suggesting antidepressants. I think my labs are odd.

Any ideas?
thanks![/QUOTE]

I would get your REVERSE T3 checked. You seem to be converting a lot of your T4-->T3, but you still feel tired. I suspect that you are also converting a lot of the T4-->Reverse T3, which blocks the effects of T3 and causes fatigue.

Pitch a fit and get your Dr. to write you a test for REVERSE T3, and you might want to add Cortisol levels, anti-thyroglobulin antibodies, and anti-TPO antibodies in as well. It shouldn't be a big deal...all the Dr. has to do is check a few boxes and fax a form to the lab.

Post your results here when you get them:)

cossette2 12-17-2008 06:40 PM

Re: Low Free T4, High free T3, normal TSH
 
The exact same thing happened to me 3 years ago when i tried Armour. My free T4 was low, my free T3 was high and my tsh was normal.

This could very well be that your adrenals are weakened. You cannot be successful taking Armour until you get that resolved. Once your adrenals are strengthened after several months, then you should try Armour.

Many doctors don't seem to understand the connection between cortisol and T3.

cossette2 12-18-2008 05:49 AM

Re: Low Free T4, High free T3, normal TSH
 
Cortisol works as a door man to allow T3 to enter the cell receptors.
Without enough cortisol the thyroid just builds in the blood looking
pretty on labs but literally not doing your tissues (where it works) any
good at all. .

Weesy 02-04-2009 02:13 PM

Re: Low Free T4, High free T3, normal TSH
 
For those who do not know, a low TSH in conjunction with a low T4 can also mean that it is not your thyroid but could in fact be a pituitary disease, generally a pituitary tumor which is not a brain tumor and are generally benign, but it's important to have your doctor do the proper testing to rule out that it isn't your pituitary causing the problem. Your thyroid can be perfectly normal and your pituitary may be causing your problems. The treatments are totally different. I would suggest you ask for a pituitary MRI to rule out a tumor.


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