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I know that usually optimal is 5080% of the range. I don't quite understand that... What I don't understand is if I have a new lab, their ranges my be totally different, but let's say I start feeling well w/ a FT3 of 350+ I don't understand how the percentages of the ranges coincide with things as opposed to say having a goal of FT4 of greater than 1.4 and FT3 of greater than 340 since all lab ranges differ.

Picture it this way: You're in school and have taken two tests.
On test 1, there were 50 questions, making each answer worth 2 points. If you got all of them correct, you scored 100%. But let's say you answered only 40 of the questions correctly. That earned you 80 points (40 x 2 = 80); therefore you scored 80% on the test.
On test 2, there were 200 questions, making each one worth only 1/2 point. If you answered all correctly, you still get 100%, just as you would have for all 50 correct answers on test 1. But if you answered 40 questions correctly on this test,, as you had on test 1, you earned only 20 points (40 x .5 = 20)  so you scored only 20% on this test. Big difference between 80% and 20%. The reason for that difference is that the "range" of questions changed from 150 to 1200. The point value changed when the "range" got broader, and so the percentage value changed.
This
should explain why your particular level's percentage is dependent on the lab range used. If it doesn't, I just wasted a whole lot of time trying to formulate a clear analogy.
If I haven't succeeded in my goal, just accept my word for it that you have to figure the percentage for each test result based on the range used for that test.
I won't try to figure doses or play the "what if" game in regard to your other questions. Thyroid treatment has many approaches. If one doesn't work after being given a fair trial for at least 23 months, it's then time to move on to the next approach. No one reacts the same way to any one method, because no two physiologies are the same. That's why analyzing numbers and comparing one patient's treatment to another's is truly futile. It takes lots of trial and error to get it right, and it's one of those things that can't be done completely by mathematical calculations.