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  • Chickenpox outbreak in highly vaccinated

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    Old 04-23-2005, 06:55 PM   #1
    1970_Torch
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    Chickenpox outbreak in highly vaccinated

    [url]http://pediatrics.aappublications.org/cgi/content/abstract/113/3/455?maxtoshow=&HITS=10&hits=10&RESULTFOR MAT=&fulltext=vaccine&searchid=107845909 7448_18659&stored_search=&FIRSTINDEX=0&v olume=113&issue=3&journalcode=pediatrics[/url]

    A case for boosters, since the first vaccine doesn't seem to work.

    Quote:
    Results.

    Of 422 students, 218 (52%) had no prior chickenpox. Of these, 211 (97%) had been vaccinated before the outbreak.

    Twenty-one cases occurred in 9 of 16 classrooms. In these 9 classrooms, 18 of 152 (12%) vaccinated students developed chickenpox, compared with 3 of 7 (43%) unvaccinated students.

    Vaccine effectiveness was 72% (95% confidence interval: 3%87%). Students vaccinated >5 years before the outbreak were 6.7 times (95% confidence interval: 2.222.9) as likely to develop breakthrough disease as those vaccinated 5 years before the outbreak (15 of 65 [23%] vs 3 of 87 [3%]).

    Conclusions.

    A chickenpox outbreak occurred in a school in which 97% of students without a prior history of chickenpox were vaccinated.

    Students vaccinated >5 years before the outbreak were at risk for breakthrough disease.

    Booster vaccination may deserve additional consideration.

     
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    Old 04-23-2005, 07:37 PM   #2
    mudhound
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    Re: Chickenpox outbreak in highly vaccinated

    I had this as an adult. BAD time!
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    God Bless

    Mudhound

     
    Old 04-23-2005, 07:42 PM   #3
    1970_Torch
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    Re: Chickenpox outbreak in highly vaccinated

    ouch!

    The kids who are getting vaccinated now will most certainly get the disease when they are adults and the vaccine's efficacy has waned.

    They will be vulnerable again in old age at which time they most likely will come down with shingles instead.

    Chicken pox is best avoided. (The vaccine or the wild virus.) That eliminates the chances of getting shingles in old age.

     
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