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Posted by doc who cares on November 06, 1999 at 13:21:23:

In Reply to: help my Mom :a cerebral lymphoma case after radiotherapy posted by liangmin on November 06, 1999 at 11:36:23:

: my mother,65yrs,be found speak vaguely the March,
: after a MRI inspection,it's be found there are two
: tumor in her brain,just beside each encephalocoele.
: she became difficult to eat and speak,difficult to
: move right arm.she had a PET inspection and found
: the high-metabolism site correlate to MRI photo.
: the local doctor regard this as a metastasis cancer
: or a lymphoma.without to fetch a biopsy,she recived
: radiotherapy,4000rad for whole brain,then 1500rad
: to the tumor position,total dose is 5500rad.finished
: radiotherapy at Jun.9.and a MRI was arranged and
: found the tumor shrinked just remain track.consider
: the tumor's position and reaction to radiotherapy,
: her doctors regards that lymphoma.she got recoved
: after that time.she can eat and speak and walk
: nearly normal during July,Aug.and Sep.these three
: month.On Oct.2,she became difficult to walk again,
: then gradually became difficult to speak and eat
: and move her right hand and leg,then left hand
: and leg.Two MRI inspection were take on Oct.4 and
: Oct.17,and can not found definite tumor.and found
: the leukoencephalopathy in her brain.Her doctor
: regards her syndrome was the side-effect of radio-
: therapy,then give her hormone(dexamethasone 10mg
: per day,i.v.on Oct.10,or one week,then 5mg per day
: ,for one week,then 3mg for one week )on Oct.10,and
: vitamin B12,vitamin c,and some drug to distend
: vessel and some drugs to nutrient brain.but my mom's
: syndrome still go in she can't walk
: can't speak,very difficult to eat,and very slow and
: difficult to response.the doctor said its rather
: rare to see such syndrome after such dose radio-
: therapy.We are in China,Who can tell me what's
: happened to my mom,and how can we save he life.
: is there some drug or method to help her? please
: tell me!thank you very very much!

: Sincerely yours
: Liangmin
your mom should be offered antiangiogenesis agents. endostatin/angiostatin in trials. i like combretastatin. chinese thunderhead god vine may also work. if the tumor is RAS, antifarnesyls should be used. in Russia, they use arglabin, from asian wormwood, with good success. and your mom should have had boron neutron capture therapyu. it is nontoxic and much more effective than conventional rays.
: .

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