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Re: Suicidally depressed - are meds making me worse?

Re: Suicidally depressed - are meds making me worse?

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Posted by Kelley on October 30, 2000 at 19:47:47:

In Reply to: Suicidally depressed - are meds making me worse? posted by Jen on October 29, 2000 at 17:22:26:

You're not alone. You have a brain chemical imbalance. Whatever it is, Effexor and Neurontin don't seem to be on target. In your shoes, I would be insisting on a new combination, one that would provide daytime energy and night time sedation. Something like Ritalin or Adderall by day, maybe just a little Effexor in the background, and a small dose (2.5mg to 5mg) of Zyprexa. Zyprexa is an antipsychotic, but don't let that word scare you. It's an awesome drug showing a great deal of promise in treating depression and mania, and has even been approved for bipolar. It can be sedating at first, so it's best at dinner. I've seen several people going nuts with treatment resistant depression get amazingly well in two weeks with Zyprexa. And you'll sleep awesome.

Another option may be something you've never heard about. The French are some of the best drug innovators in the world. They have one called Adrafinil. In Europe they claim it is far superior to Prozac. Here in the USA a close cousin called Modafinil has been approved. But Adrafinil is far superior and about ten times cheaper ($25 a month). What does it do? After about a week you begin to regain interest in activities. You start getting more involved and more talkative. After two weeks depression lifts. At three months cognitive enhancement is experienced, i.e. better memory, quicker thinking, etc. It works even with normal people, resulting in more interest and more energy. Unlike stimulants per se, it works slowly over days, weeks, and months. Just an option to know exists. Do a search on Adrafinil and you'll find sources to mailorder it. No prescription needed.

A doctor visit seems warranted though. If the current drugs are cutting it, insist on some new ones. Try some from different classes. I really like what I've seen with other drugs, when normal antidpressants didn't cut it. Small dose Lithium, benzos, small dose antipsychotics, small dose stimulants (heck, they give em to children, right?), all these things can work wonders when things that are supposed to work don't. I don't mention anything that I haven't actually tried myself. I'm familiar with all of these.

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