I highly doubt the cure is going to be in topical form. I believe it has to be cured from the inside-out, and not by direct skin application. What happens when you stop using the topical or your skin becomes immune to it? All acne combatant topicals contain a drying agent (BP, Tea Tree Oil, Salicyclic (sp?) acid, etc). Accutane is the closest things to a cure, and it's a pill, and has proven to be very effective long-term.