In my opinion hormonal acne has nothing to do with whats on the outside, meaning cremes. Hormonal acne is controlled by testing for pcos, and taking birth control with spiro (hormone blocker) or accutane. Antibiotics only do so much and birth control too, but it's temporary. Read the spiro posts and see about that particular drug. Accutane drys up the oil but i don't think for some that it is permanent.