I've been on 2 drugs that stop acid for about 3 and a half months now, and have wondered if they are dangerous to stay on for a few months longer. I didn't have refulx, but was seriously inflammed inside due to Celiac Disease (an intestinal/autoimmune disorder) so I began taking Aciphex and Bentyl. I take the Aciphex once a day and the Bentyl 3x a day. So far my GI doc hasn't said a thing about these drugs hurting me, and he continues to give me refills. I have noticed that when I miss a pill or haven't picked up my refills in time to take it, that I feel crampy and terrible inside...this makes me wonder if I'll ever be able to tolerate going off these drugs. I wonder how bad they are, exactly, but also wonder why if they are so bad why our doctors would continue to refill them endlessly?!