My doctor has had me on Aciphex for the past 3 months. The other day I asked him if it was safe for me to continue taking it and my other drug, Bentyl, because it had already been all those months, and he replied that it was ok "for the rest of my life." This is totally different from everything else I've read on this board concerning PPIs. How safe/dangerous are PPIs, anyway? the doctor said Aciphex has been studied in people who've used it for years without side effects being reported. I don't know what to believe.