YES! Spiro works! If you are a girl, it works best with contraceptives. I was only on 25mg...and it took all the oil away. I was off of it for like 2 weeks because I had run out and my doctor had to check my blood before giving me a new prescripition, and during that 2 weeks, my face was oily again. But I didn't have any crazy break outs or anything...but it really does the trick. I am now on 50mg, 1 in the morning and 1 before 5. My doctor even gave me 2 refills, I guess she wanted to see how things worked before allowing me to get refills. But yes, I do recommend it. I have been on contraceptives for 2 months now (generic orthotricylecen-it's called TriSprintec and has worked well!!), retin-a micro for 2 months (at night), benzaclin for 5 months (in the morning). I use cetaphil gentle cleanser morning and night with a warm cloth and water to wipe excess skin off my face and in the mornings I apply cetaphil moisturizer after the benzaclin. I am 24 and have had acne since about 13 to 14. MY FACE HAS NOT LOOKED SO GOOD! All the best!!