Hi All, I will be 23 soon so I guess I'm getting closer to being in the "adult acne" category. I've had acne since I was 10 yrs. old. I tried all the OTC products before getting serious help, at which time I tried a line of prescriptions: Benzamycin, Minocyclin, Differin, Benzaclin, Retin-A Micro, Tazorac...Ortho Tri-Cyclen, and now Yasmin. My acne has affected me emotionally at a deep level. I've never been extremely depressed, but I do have terribly low self esteem. I hate making eye contact, and when a boyfriend or a friend tells me I'm beautiful, I find it soooo hard to believe them. I look in the mirror and laugh or cry, depending on my state of mind. Right now I have cystic acne mostly along my chin and lower cheeks, with sporadic ones on my forehad and cheekbones. I'm feeling extra repulsive right now because --I swear-- there is like a clump of 8 monster cysts on the right side of my face all in close proximity. It is mostly moderate, but always there. The severity comes and goes, but this is the worst its been in awhile. Its hard to know where to turn or what to try next. Will it all just be more money down the drain? I try to stay positive despite how I sound right now. A lot of times I just try to hide my pain. So, next on the list...I'm trying to look into Spiro. I would never have known about it unless I read this board & hopefully I can get a prescription and try it out. I wish you all success and courage...for this fight is so hard to win!