I began taking Nexium (the purple pill) for reflux about two weeks ago. Since them I have awoken three times with swelling in my upper or lower lips. After the Benedryl treatment it goes away in about 8 hours. I have not eaten anything different during this period. I am also taking Celebrex and Neurontin for a back conddition but have been on these meds for about a year. Has anyone had an adverse reaction to Nexium?