I know how you feel, Graferman. Once one of my cystic acne spots would clear up, another one would appear. I just couldn't win. After a few years of Tetracycline, Minocycline, benzoyl peroxide, clindamycin, differin, and the list goes on....I finally went on Accutane. I'm at the beginning of my third month and I can't even begin to tell you how amazing it's working for me. Aside from one horrendous cyst that went away and came back, I haven't had one cystic breakout. As a matter of fact, nothing has appeared on my face. The blackheads on my nose and chin all came out and my face is completely smooth. I'd recommend Accutane to anyone who has to deal with cystic acne.