My pills I take are sinemet 25/100 4+ a day, sinemet 50/200 4+ a day, comtan 200mg 4+ a day, mirapex 1mg ONLY 4 times a day and ritalin (suppose to take 5 a day I take 2) When I went off ritalin (doctors orders) I found that I had real bad freezing spells, 5-6 hrs Laid on a floor. Went back on ritalin no more major freezing spells. Had parkinson for 10 plus years I'm 50 now. Talk to your doctor about supplement CO-Q 10. Hopes this helps.