Discussions that mention diazepam

Pain Management board


Hey mary, Baclofen is for muscle spacticty, a little different from spasms, Spacticity is when the muscles become rigid and spastic, like you would see with wheelchair bound patients, MS and some other conditions. However it does have some pain relieving qualities and can be a good adjunct med with pain meds and will help with plain muscle spasm.

You have searched for drug interactions between the following drugs: Soma,baclofen,Valium

Please note: only generic drug names are displayed.

We did not find any drug interactions between the following drugs: Soma,baclofen

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diazepam (moderate Drug-Food)
Description:

MONITOR:
Grapefruit juice may increase the plasma concentrations of some orally administered drugs that are substrates of the CYP450 3A4 isoenzyme. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits. The extent and clinical significance are unknown. Moreover, pharmacokinetic alterations associated with interactions involving grapefruit juice are often subject to a high degree of interpatient variability.

MANAGEMENT:
Patients who regularly consume grapefruits and grapefruit juice should be monitored for adverse effects and altered plasma concentrations of drugs that are metabolized by CYP450 3A4. Grapefruits and grapefruit juice should be avoided if an interaction is suspected. Orange juice is not expected to interact with these drugs.




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Please note: only generic drug names are displayed.

diazepam and carisoprodol (moderate Drug-Drug)
Description:

MONITOR:
Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT:
During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be made aware of the possibility of additive CNS effects (e.g., drowsiness, dizziness, lightheadedness, confusion) and counseled to avoid activities requiring mental alertness until they know how these agents affect them. Patients should also be advised to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.




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Please note: only generic drug names are displayed.

diazepam and baclofen (moderate Drug-Drug)
Description:

MONITOR:
Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT:
During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be made aware of the possibility of additive CNS effects (e.g., drowsiness, dizziness, lightheadedness, confusion) and counseled to avoid activities requiring mental alertness until they know how these agents affect them. Patients should also be advised to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
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Hey mary, the safest interction looks like Baclofen and Soma, when you add Valium to the mix you get combined CNS depression, which is what puts you to sleep. That one good night ofsleep where you feel better, ma be more active and prevents you from taking naps in the day from not sleeping, ismay allow the soma alone to work. Particularly if your napping in the daytime. That really throws you sleep off at night.
The meds and doses are relatively safe though, IF you had said 4 soma and 30 mgs of valium I would be concerned but your not taking more of any med than your used too , rather combining doses you have been previously exposed too.

I don't know if a doc would recomend combining meds for sleep but you know what works in a clinch. As far as CNS interaction, you are pretty much used to them , If you added meth to the interaction list, it would be another CNS depressant. But you have been doing fine so far and so have many others that take a combination of CNS depressant, Pan meds, muscle relaxers, antiseizure meds etc. It seems Baclofen doesn't have as much CNS depressant effect as Valium and Soma.
When is the surgery and good luck, Dave
Diazepam has a long 'half life' in the body, meaning it one of the class of benzo's which take the longest time period to be eliminated from the body (and central nervous system.)
By also taking the S - you are in effect taking two drugs which in essence have the same result, except that the S has an extremely short 'half life' elimination period in the body so be extremely cautious, knowing that you are taking two sleeping med's at the same time. The short acting that these (benzo) drugs are, the sooner you will crave higher and higher doses and the sooner you can find yourself feeling awful withdrawal symptoms if you do not keep on taking higher doses or try to stop using it. If there is no other way for you to get some sleep then why not rather increase your diazepam dose and not mix two seperate sleeping med's.
Once you decide that you no longer need to take the diazepam - if you taper off it slowly over time in small steps you can come off it without major withdrawal effects. I would seriously consider stopping the other sleeping med!
Good luck with your operation.