I WAS on toprol xl 100mgs, verapamil 240mgs, lisinopril 40mgs, hctz 25 mgs and ecotrin 325 mgs all for bp. That doesn't cover my diabetes or thyroid problem. Yeas it did lower my bp to about 113/72. BUT i suffered so with side effects that i am now on 240 verapamil, 325 mg ecotrin and 12.5 hctz. im suppose to take 150 avapro, but im not. I will start after seeing my new dr and hopefully a cardio. At one point i was on 24 pills, including lipitor.