Yes, it happened to me. I was so depressed after I had my first baby it lasted a year. I actually thought it was something other than depression and talked to my OB/GYN about it and he knew instantly, I guess it happens often enough. I was first put on Zoloft and it made me manic and gave me quite a sex drive but problems with orgasm. Then I tried prozac and lexapro and did better but not perfect. Now I am on the Emsam patch, there are no sexual side effects with it and it does not give me insomnia so I am doing better.