Discussions that mention enbrel

Arthritis board


The drug Indomethacin is used to treat moderate to severe ankylosing spondylitis, usually in the beginning stages. So that is good news. This should calm alot of your symptoms. It does take some time for this drug to start working tho and may not work at all. If not there are many other drugs to try.

NSAIDS (Indocin, Voltaren, Naprosyn, etc.) Note: Cox-2 inhibitors such as Celebrex and Vioxx are considered a sub category of NSAIDS. All of these are non-steroidal ani-inflammatory medications.

DMARDS (Methotrexate, Sulfasalazine, Arava, Cyclosporin, etc) These are disease modifying anti-rheumatic drugs.

TNF Medications (Enbrel, Remicade)
These medications help control the amount of TNF (tumor necrosing factor) in the joints.

Muscle relaxers will generally not have much effect on your condition since it isn't muscle related. Altho the other symptoms you may have reflect fibromyalgia, it is truly not fibromyalgia. The symptoms you describe are all in line with ankylosing spondylitis. AS is a painful, progressive, rheumatic disease. It mainly affects the spine but it can also affect other joints, tendons and ligaments. Other areas, such as the eyes, lungs, bowel and heart can also be involved.
If a parent has AS there is a 50% chance that the B27 gene will be passed on to a child. However, not everyone with the B27 gene will go on to develop AS. Overall, the likelihood of your child developing AS will be less than 1 in 10 (or 1 in 5 if B27 positive).

AS seems to affect everybody slightly differently. In general, though, you will probably find that the symptoms come and go over many years. In the classic case, the lumbar spine can become stiff, caused by the growth of additional bone, as can the upper spine and neck. If you pay attention to your posture, exercise regularly and avoid the stoop associated with the condition, you can prevent this from becoming too serious.

So as time passes, different treatments will be needed.

The most promising new treatment is Remicade. It was originally used for chrohns disease but is showing substantial results for people with AS not only to relieve symptoms but to stop the progression of the disease. Most insurance carriers will pay for this if it's shown that nothing else will help(that is also changing). It is quite expensive.

Even though ankylosing spondylitis is incurable, 85 per cent of people have nothing more than a mildly stiff back after the initial painful start of the disease. Unless the hips and knees are affected, almost no disability results. Only five per cent of people who have the disease become severely disabled.

Most importantly remember to excercise everyday and take your medications. Your doctor is your partner in this. Try and find one you feel comfortable with.

Good luck with this. I have much hope that his drug you're getting will work for some time and you can return to your normal life. :)