Discussions that mention enbrel

Back Problems board


Regarding ENBREL

I had not heard of this medication until very recently. Have done a bit of research and there certainly are medical case studies that show that the drug can dramatically improve discogenic pain. Am not sure what the risks are and why my pain mgmt doctors have not mentioned this to me as an option. Will grill them about it when I see them this week and report back.

--tennisnut

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1. Lower back pain started 9/2002. No traumatic injury. Avid recreational tennis player (4-5X/week) and downhill skier. Also enjoyed biking and hiking.
2. First 3 months after initial pain did NOT listen to my body and continued to activities that worsened pain.
3. 1/2003 MRI shows disc protrusion/herniation at L5/S1 (midline). Also shows degenerative endplate changes, loss of disc signal intensity (DDD).
4. 2/2003 Caudal epidural injection fails. Multiple anti-inflammatories fail. 5. 2/2003-5/2003 2x week PT. Stopped sitting for work. After several months, PT agrees that treatment is making me worse. Any extension exercise (e.g. Mackenzie)makes symptoms much worse.
6. 4 Orthopedic and neurosurgeons say fusion or ADR my only hope.
7. 6/2003 Started taking Neurontin 900mg tid. Did not think drug was helping until I stopped taking it and pain went through the roof. Does seem to reduce pain by 2 points.
8. 6/2003 Visit with Dr. Jeffrey Saal to discuss IDET. Dr. Saal says my disc is on its “last hurrah.” Has been degenerating for many years, but my body has adapted. Thinks that I will be pain free once last bit of hydrated portion of disc (nucleus) has leaked out. Refers me for bi-lateral selective epidural injections.
9. 8/2003 Pain clinic performs interlaminar epidural--no relief; 9/2003 Pain clinic performs selective (transforaminal) injections—no relief.
10. Discogram on 10/13. Results show condordant pain at L5-S1 at low pressure, Grade V annular tear, 50% loss of disc height. No leakage aside from annular tear.
11. Based on estimate from IDET expert of 50-50 chance (conservative guess)of good outcome, will schedule procedure.
Correction my my earlier post:

The medication is called ENBREL.

--tennisnut

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1. Lower back pain started 9/2002. No traumatic injury. Avid recreational tennis player (4-5X/week) and downhill skier. Also enjoyed biking and hiking.
2. First 3 months after initial pain did NOT listen to my body and continued to activities that worsened pain.
3. 1/2003 MRI shows disc protrusion/herniation at L5/S1 (midline). Also shows degenerative endplate changes, loss of disc signal intensity (DDD).
4. 2/2003 Caudal epidural injection fails. Multiple anti-inflammatories fail. 5. 2/2003-5/2003 2x week PT. Stopped sitting for work. After several months, PT agrees that treatment is making me worse. Any extension exercise (e.g. Mackenzie)makes symptoms much worse.
6. 4 Orthopedic and neurosurgeons say fusion or ADR my only hope.
7. 6/2003 Started taking Neurontin 900mg tid. Did not think drug was helping until I stopped taking it and pain went through the roof. Does seem to reduce pain by 2 points.
8. 6/2003 Visit with Dr. Jeffrey Saal to discuss IDET. Dr. Saal says my disc is on its “last hurrah.” Has been degenerating for many years, but my body has adapted. Thinks that I will be pain free once last bit of hydrated portion of disc (nucleus) has leaked out. Refers me for bi-lateral selective epidural injections.
9. 8/2003 Pain clinic performs interlaminar epidural--no relief; 9/2003 Pain clinic performs selective (transforaminal) injections—no relief.
10. Discogram on 10/13. Results show condordant pain at L5-S1 at low pressure, Grade V annular tear, 50% loss of disc height. No leakage aside from annular tear.
11. Based on estimate from IDET expert of 50-50 chance (conservative guess)of good outcome, will schedule procedure.
Hi Tennisnut--I've tried a few times to go to the link on Enbrel you posted above, but I keep getting "page not available" messages. I've approached it through a few different platforms, but it still could be a quirk in the system. But if you have a moment to check the link is correct, would be appreciated.

BTW, this has been a very valuable thread--thanks to you and all for sharing your stories and suggestions. I fully appreciate your wish to get things resolved, but also glad to hear there are folks like Dr. Saal who are ready to recommend the "wait it out" option as well.

Best,

Standingman
Hi tennisnut,
Thanks for the info on enbrel... that sounds very interesting!!! Standingman, cut and paste the link into a new browser window, and then delete the final period "." at the end of the "PDF" in the URL. That leads you to the article... and a very interesting one it is!

And tennisnut... good luck with your IDET!

[img]http://www.healthboards.com/ubb/heart.gif[/img] Telzey