Discussions that mention fluvastatin

High Cholesterol board


I think you need to lose weight, exercise more and eat very healthy, avoid junk food. Here is some info about statins.

Pharmaceutical companies have concocted a variety of drugs collectively known as “statin drugs,” the most popular being lovastatin, pravastatin, simvastatin, and fluvastatin and fibrates. Their effect is one-dimensional; lower cholesterol levels by decreasing the body’s ability to synthesize
it. Even worse, their use has been linked to undesirable side effects such as stomach, liver, and lung tumors in mice (reference). Lovastatin reduces levels of coenzyme Q10 and L-carnitine, two very important molecules involved in energy production and fat metabolism (Mortensen et al. 1997). Forty-five hyper-cholesterolemic patients were randomized in a double-blind trial were taken either lovastatin (20-80 mg/day) or pravastatin (10-40 mg/day) over a period of 18 weeks (Mortensen et al. 1997). Serum levels of coenzyme Q10 were measured parallel to the levels of cholesterol at baseline on placebo and diet and during active treatment. A dose-related significant decline of the total serum level of coenzyme Q10 was found in the pravastatin group In another study forty-seven patients were treated with 10 or 20 mg of Simvastatin per day for 14 weeks. As expected, total cholesterol and LDL cholesterol concentrations decreased considerably, but unfortunately, the decline in circulating vitamin E and coenzyme Q10 concentrations were also documented. The five hospitalized patients, 43-72 years old, revealed increased cardiac disease from lovastatin, which was life threatening for patients having class IV cardiomyopathy before lovastatin or after taking lovastatin (Folkers et al. (1990). Lovastatin was shown in some patients develop a secondary deficiency in muscle carnitine. Clinically, this may
manifest as a myalgia/myositis. Myalgia refers to generalized muscle pain, may
accompany myositis, which is inflammation of the muscles, either in response to an immune system disorder refers to inflammation of the muscles. Treatment with lovastatin significantly alters the carnitine. The use of statins or statins containing products such as Meniscus purpureus (known as “red rice yeast”) in treatment of high cholesterol could lead to a secondary deficiency in carnitine, which may manifest clinically as a myalgia/myositis-a side effect that is occasionally seen with this class of drugs.
Quote from sallyko:
I think you need to lose weight, exercise more and eat very healthy, avoid junk food. Here is some info about statins.

Pharmaceutical companies have concocted a variety of drugs collectively known as “statin drugs,” the most popular being lovastatin, pravastatin, simvastatin, and fluvastatin and fibrates. Their effect is one-dimensional; lower cholesterol levels by decreasing the body’s ability to synthesize
it. Even worse, their use has been linked to undesirable side effects such as stomach, liver, and lung tumors in mice (reference). Lovastatin reduces levels of coenzyme Q10 and L-carnitine, two very important molecules involved in energy production and fat metabolism (Mortensen et al. 1997). Forty-five hyper-cholesterolemic patients were randomized in a double-blind trial were taken either lovastatin (20-80 mg/day) or pravastatin (10-40 mg/day) over a period of 18 weeks (Mortensen et al. 1997). Serum levels of coenzyme Q10 were measured parallel to the levels of cholesterol at baseline on placebo and diet and during active treatment. A dose-related significant decline of the total serum level of coenzyme Q10 was found in the pravastatin group In another study forty-seven patients were treated with 10 or 20 mg of Simvastatin per day for 14 weeks. As expected, total cholesterol and LDL cholesterol concentrations decreased considerably, but unfortunately, the decline in circulating vitamin E and coenzyme Q10 concentrations were also documented. The five hospitalized patients, 43-72 years old, revealed increased cardiac disease from lovastatin, which was life threatening for patients having class IV cardiomyopathy before lovastatin or after taking lovastatin (Folkers et al. (1990). Lovastatin was shown in some patients develop a secondary deficiency in muscle carnitine. Clinically, this may
manifest as a myalgia/myositis. Myalgia refers to generalized muscle pain, may
accompany myositis, which is inflammation of the muscles, either in response to an immune system disorder refers to inflammation of the muscles. Treatment with lovastatin significantly alters the carnitine. The use of statins or statins containing products such as Meniscus purpureus (known as “red rice yeast”) in treatment of high cholesterol could lead to a secondary deficiency in carnitine, which may manifest clinically as a myalgia/myositis-a side effect that is occasionally seen with this class of drugs.


Thanks for the info sally, but that is waaay, waaay over my head. I'm glad to see that lipitor isn't in that list at all. I do realize that statins do have their dangers, ALL meds have their dangers. But high cholesterol has dangers too. As I said though, I thank you for your post. :)