Discussions that mention gemfibrozil

High Cholesterol board


From the Crestor website and prescribing information for physicians.

Important safety information about CRESTOR

CRESTOR is prescribed along with diet for lowering cholesterol and is not for everyone, including people with liver disease, and women who are nursing, pregnant or may become pregnant. Tell your doctor promptly if you experience unexplained muscle pain or weakness, as they may be a sign of serious side effects. Be sure to tell your doctor about other medications you are taking, including cyclosporine, warfarin, gemfibrozil, or antacids. Simple blood tests are needed to check for liver problems before and 12 weeks after start of therapy or change of dose, and periodically, eg, semiannually thereafter. Side effects occur infrequently and include muscle aches, constipation, weakness, abdominal pain, and nausea. They are usually mild and tend to go away. CRESTOR has not been shown to prevent heart disease or heart attacks.

I wonder how many physicians actually advise their patients to do this prior to starting statin drug therapy.

PRECAUTIONS

General

Before instituting therapy with rosuvastatin, an attempt should be made to control hypercholesterolemia with appropriate diet and exercise, weight reduction in obese patients, and treatment of underlying medical problems (see INDICATIONS AND USAGE).