Discussions that mention humira

Arthritis board

Hi there. Like you, I am negative for the rheumatoid factor, but have persistently high erythrocyte sedimentation rate & C-reactive protein (both are markers for inflammation). My rheumatologist is treating me for seronegative rheumatoid arthritis. I am presently taking methotrexate, but will likely begin a course of Humira shortly.

So...it is possible to have RA without testing positive for the rheumatoid factor. Hopefully, your doctor will treat you aggressively so you can avoid joint damage.
I have been diagnosed for about two years...all started from some unexplained aches and pains in my joints and funky bloodwork. My primary doctor originally thought lupus becasue my ANA was high as well as my ESR and CRP. I also had a strange rash on my face. My ANA has since normalized and the other more lupus-specific tests were negative. My rheumatologist says diagnosis is often one of exclusion. After much testing and symptom following, RA "fits."

The mobic you are taking is a NSAID, similar to diclofenac, alleve, etc. Thus, you are presently being treated with an antiinflammatory. My rhematologist put be on a similar drug called Daypro. He also started me on a drug called sulfasalazine and gave me a prescription for prednisone for acute flareups.

As this treatment did not eliminate symptoms, he added methotrexate, which has seemed to help some. However, given my age, 32, he'd rather treat aggressively, as my joint damage at this point is minimal. Hence, the humira, which I'll begin this month. (Humira works similarly to enbrel and remicade. These are very expensive drugs, so you will likely go through a course of all of the aforementioned "cheap" drugs first).

Humira and methotrexate are in a class of drugs called DMARD's. They suppress your immune system by various mechanisms, thereby reducing the inflammatory process and joint damage.

RA is a very treatable disease now, so don't panic. Let us know how you're doing when you see the rhematologist.

In the meantime, if you have questions, post on the board. I'll check in periodically. Good luck. :)