Discussions that mention kineret

Fibromyalgia board


Okay, Blue, here is the info about Humira, and at the end, I'll list the "Self-care" remedies rated most popular by RA patients.

First let me say, I found that Humira is very similar to Remicade as far as it's components. Humira is administered the same way Enbrel is, tho, Humira does not need to be injected as often as Enbrel. I also found a "warning" by Abbott Labs, the manufacturerer of Humira in regards to an adverse reaction with a certain medication that is used to sometimes treat RA and Cancer patients. I will also list info about that interaction. Though the other RA treatments like Remicade and Enbrel boasted that they work well with other meds. This is the only treatment I found that adversely interacts with this one particular medication. Although, like many medications, there are always precautions and drug interactions that are listed when you recieve your prescription. We all know that we should read that paper, tho a lot of us don't (raising my hand! ). The one "precaution" that kept popping up referred to anaphalaxic as one of those precautions. We also know that you should talk in depth to your doctor about ALL possible reactions and side effects you may experience with any of these treatments.

HUMIRA is a biologic disease-modifying medicine that interrupts the inflammation process and helps slow the progression of rheumatoid arthritis (RA). The active ingredient resembles an antibody that normally occurs in your body, so it helps your body to fight RA the way it would if it could. HUMIRA can also be taken with pain medications and other disease modifying drugs. It resembles antibodies normally found in the body. As HUMIRA binds and blocks the activity of TNF-a, it reduces the signs and symptoms of RA and slows the progression of structural joint damage caused by the disease.

How is HUMIRA different from other medications that treat RA?
HUMIRA is a biologic disease-modifying antirheumatic drug, also called a DMARD. Biologic DMARDS (DMARDS were mentioned in the first couple of my posts referring to the info of how these treatments work ) are among the most recent RA treatments approved by the FDA and are approved for reducing the signs and symptoms, and slowing the progression of structural damage to the joints caused by RA.

Other biologic DMARDs include EnbrelĀ® and RemicadeĀ®. Enbrel is injected once or twice weekly, and Remicade requires a visit to the doctor to administer the medication. HUMIRA is an effective biologic DMARD and was the most widely studied TNF-a antagonist when it was submitted to the FDA.

HUMIRA can be injected by you or a loved one in the convenience of your own home. And, it usually only needs to be taken once every two weeks - giving you more freedom to live your life without having to always think about taking your medication.

The most common side effects of HUMIRA are:
injection site reactions
upper respiratory and sinus infections
headache
rash
injection site pain

Anakinra
A substance that is used to treat rheumatoid arthritis, and is being studied in the treatment of cancer. Anakinra blocks the action of interleukin 1 (IL-1). It belongs to the family of drugs called interleukin receptor antagonists. Also called KinaretĀ®. (interleukin is one of the protiens referred to in my thread about FM being classified as a disease. This protien is one of the protiens that, when elevated, "poison" your immune system, which regarding FM, damages the neurotransmitters that are meant to block pain. Often when your doc orders a CBC to check your blood, there is a section in the test that reads protien levels, it is normal to see elevated protien levels in FM, RA, Lupus and MS patients )

Use with Anakinra This is taken from the Precautions and Drug Interactions sections of the information literature that is packaged with Humira.
Serious infections were seen in clinical studies with concurrent use of nakinra
(an interleukin-1 antagonist) and another TNF-blocking agent, with no added
benefit. Because of the nature of the adverse events seen with this combination therapy, similar toxicities may also result from combination of anakinra and other TNF blocking agents. Therefore, the combination of HUMIRA and anakinra is not recommended (see PRECAUTIONS, Drug Interactions). Remember, I said that reports of anaphylaxis was found in reference to the list of severe side effects of any of these treatments. Again, you know to speak in depth to your doctor regarding any of these treatments and their possible side effects. I'm not promoting any particular treatment, I am merely offering you information that is available to the public, your doctor knows you best and will know which is best for you.

Okay, enough of the technical stuff, here comes the info from a group of your "peers". LOL Sounds like a game show! Here's the top rated self treatments for RA, rated by other RA patients. There is only one list of preferred prescription meds by other RA patients.

The numbers next to the "treatment" are the rating value from 1 thru 10. 10 of course being the best.

Self-care Treatments: Top 3 Remedies
Laughter / Humor Therapy: 10 Blue, I think you've got this one covered!
Patient Education: 9.6 The list of education may not have been approved by board policy, so I'll just say that "self-education" by any means you have available is always a 10!
Hydrothermal Therapy: Sauna / Steam Baths: 9.3

Nutritional Supplements Top 3 Remedies
MSM (Methylsulfonylmethane) 10
Vitamin C (Ascorbic Acid) 10
Multi-Vitamin; Mineral Supplements (combined ratings)

Complementary and Alternative Therapies Top 3 Remedies
Bodywork Therapies: Jaffe-Mellor Technique 8.4 I have NO idea what type of therapy this Jaffe-Mellor Technique is! Anyone know?
Bodywork Therapies: Therapeutic Massage: 7.8
Chiropractic Therapy 6.8

Over-the-counter Medications and Products Top 3 Remedies
Therabath etc. (Paraffin Wax Baths) 9.2
Magnetic Therapy: Pulsed Magnetic Fields (PMF) 8.9
Topical Painkillers: Methyl Salicylate Formulas 8.3

Prescription Medications and Doctor Procedures Top 3 Remedies
Solganal (Aurothioglucose) 9.7
Flexeril etc. (Cyclobenzaprine) 9.7
Methadone etc. (Methadone Hydrochloride) 9.3


AND FINALLY! Here is a list of the most popular RA specific treatments:
Top 10 Remedies for Rheumatoid Arthritis Remedy Name Weighted Rating
(0 = poorest; 10 = best)


Antibiotic Therapy 8.1
Enbrel (Etanercept) 7.2
Remicade (Infliximab) 6.9
Deltasone etc. (Prednisone) 6.8
Plaquenil etc. (Hydroxychloroquine) 6.3
Rheumatrex etc. (Methotrexate) 5.9
Arava (Leflunomide) 5.8
Celebrex (Celecoxib) 5.5
Kineret (Anakinra) 5.2
Azulfidine etc. (Sulfasalazine) 4.2


Okay, there ya go! Keep us posted on how your treatment goes, whichever one you choose. You too Glojer.

Love to you!
tk