I have been taking Lanoxin for years, and I have always told my husband that I think the Lanoxin was making me short of breath. I only got short of breath after I started taking these heart medicines. But I am afraid to get off them myself and of course the Dr. says no to taking me off them and just keeping an eye out. Please write a note if you also experience this since taking Lanoxin and I will bring it up again on my visit to him.