I've been on Lotrel for about a year. Recently (3 weeks ago) my doctor increased my dosage from 5/10 to 10/20. I've noticed some urinary problems usually early in the morning only. I feel like I have to urinate badly but it takes a while to start and then it goes on forever. When I think I've finished, I urinate more. I've also noticed my ankle swelling slightly at end of day. I thought the urinary problem was related to a gynecological problem I've had but my gynecologist doesn't think so. Do you think it's from the increased dosage of Lotrel? Anyone else have a similar problem?