Topamax has been a blessing for me. My pain Doc started me on it a little less than a year ago. In the last 20 some years I have tried several of the common drugs for neuro pain, including amitrytapline (Elavil), Neurotin, and recently Lyrica. The Elavil worked well but caused serious weight gain. Neurotin and Lyrica caused me to have intense, extremely vivid dreams but did little for pain control. The Topamax has worked well in controlling the pain due impingement of both L5 nerve roots. Yes, it did cause some weight loss. That in itself helped me, as I needed a few pounds off. I didn't have any significant side effects. There has been some evidence of increased possibility of kidney stones with Topamax, which is of interest to me since I have been down that road. Interestingly enough, since I have been on Topamax I passed a stone and didn't even know it. It worked that well on pain control. I just have to remember to drink more, something I am not very good at doing. As with any drug, talk to your doc and pharmacist. Your pharmacist can be a wellspring of information. Best of luck.