kim...hi...well let tell you what happened to me when i tried that before you do!...im detoxing now from oxycontin...a few years back i was on methadone and was prescribed effexor for depression, i then did a rapid detox and never depended on anything again..until oxycontin came along...i started abusing drugs at a very young age..now im 29 on my 4th day no oxy...from 240 mgs a day to zip/zero...sick but hanging in there, the first time i tried to detox i went into medicine cabinet and took out the effexor, (this was in the first day or 2 of withdrawl) popped a effexor in mouth and went for a ride with my fiance to smoke cannabis (seems like its the only thing that makes me feel somewhat comfortable during withdrawl, and a little hungry although cant hold much food..)...once we got back to my place about 1 hour later i stepped out the car and took about 6-7 steps and fell flat on my face, just dropped passed out, doc said the effexor would do that, it does work for depression but i wouldnt take it unitl the withdrawls went away...anyway good luck!