I have recently been diagosed as anemic after starting on methotrexate for my rheumatoid arthritis. My hemoglobin had been slowly dropping for over a year but took a serious nose dive as soon as I started the methotrexate in November 2004. When it went from 11.7 to 10.2 in less then two weeks the rheumatologist sent me to the family doctor who put me on Niferex 150. But the strange thing is as soon as hemoglobin dropped I started feeling great. I mean I felt GREAT. As soon as I started on the iron my energy level dropped and I was exhausted, I was taking two naps a day. I lasted on the Niferex for two days and quit taking it. Serveral days later, after talking to the pharmacist, I switched to Niferex Forte taking it with meals. That lasted five days. Went off it for four days and tried again for another four days before quiting again. I have tried over the counter iron tablets, ferrous sulphate 27 mg., it all makes me tired and I feel beat up. My hemoglobin is down to 9.55, hematocrit is 33.2. Iron is 21, saturation is 5 and ferritin is 3. I don't know what this stuff means but if I feel fine I don't understand why I need to take iron. I do take a multivitamin with 18mg of ferrous fumarate and have for the last six months. I am not normal, I have never been normal but the doctors refuse to look for zebras, insisting that there are horses back there somewhere. Has anyone else ever had this problem with iron before? Am I that abnormal? I would love some feedback. Thanks.