[QUOTE=sunshine8790;3351401]Was diagnosed with RA a few months ago, just started methotrexate on Friday and I've been so sick to my stomach I can't stand it.
How long does it take for mtx to work?
Well it usually takes six to 8 weeks to feel some effects although it hasnt been helping me much. I have RA for many years and alreadly had a total knee replacement 12 years ago at age 36. I started on enbrel 3 weeks ago and still taking all my other meds until I see my rheumatologist in January. Currently I am on methotrexate,plaquenil,azulfidine, folic acid and enbrel.