Oh yes. I gained alot of weight too from the Neurontin and Lyrica. I could have just eaten more because of sitting around too much but my appetite was out of control. I am post gastric bypass so it was very disturbing to me. Finally my Dr. changed me to Topamax. The side effect with that is weight loss. I think 5lbs or something. Nothing exciting. I still feel swollen though. Not sure if from that or another med. The Lyrica and Neurontin caused me to retain water too.