Discussions that mention norvasc

High & Low Blood Pressure board


Also I'm thinking about switching from Diltiazem SR to Norvasc 5mg. Actually, it's good to take Norvasc once daily instead of the 2 dose daily of Diltiazem SR. I tried Norvasc before but didn't give it time to work, only for few days and I stopped it.
Does anyone knows the difference between those?
Do I have to wean off Diltiazem? or I can stop it today and start Norvasc tommorow.
Thanks,
Michael
Hi Michael,

Diltiazem should be tapered over a couple of weeks or longer under your doctors' supervision. I forget how large a dose you've been taking. Don't do what I did and stop it abruptly. Doing so will affect your heart's conduction system and is very dangerous. I have been on a maximum dose and found it impossible to stop this drug after a few attempts. I think these withdrawal effects are dose-related, so lower doses should be easier to discontinue. Be careful.

With Diltiazem, peak plasma levels are reached in 2-4 hours, while Norvasc takes a bit longer -6-12 hours. I have been looking into switching back to Norvasc because it has generally fewer side-effects. The incidence of edema is lower. When I was on Norvasc, I didn't have the edema problems. It seems though that I am stuck with Felodipine for now.

Zebeta (Bisoprolol) 1.25mg is a baby dose. You should be OK with few or no side effects. I am on this drug also. This beta1 blocker does not seem to bother me as much as the beta2 I took previously did.

Instead of starting Norvasc at 5mg, why not start it at 2.5mg? Remember, you want to keep the side effects to a minimum and the 2.5mg dose might be enough. With Norvasc, you have to wait at least 7-8 days of consecutive dosing to see if it works. (Don't skip days!!!) You can expect a reduction of 13/7 or so in your pressure if your hypertension is moderate (sorry, I don't remember).

There could be minor interactions between the drugs mentioned. You are taking fairly low doses of these meds, so I doubt you'll have any problems. Things to watch for: your serum potassium and blood glucose should be monitored when Hctz is combined with Bisoprolol.
Norvasc and Bisoprolol - there may be additive reductions in heart rate, cardiac conduction and contractility - contact your doctor if any problems or heartbeat too slow.
Hctz with Norvasc - antihyperensive effect could be additive.
I don't think you'll have any problems because of the low doses. Always contact your doctor if not sure and report adverse reactions and/or side effects.

Good luck! :)

flowergirl
flowergirl,

Thank you very much for your help. My blood pressure is 140/100 from Nov to the end of April or even after that. So you want me to wean off Diltiazem while starting to take 2.5mg Norvasc + 1.25mg of Zebeta + HTC 6.5mg ? then in 2 weeks I would be on the 5mg of Norvasc plus the 1.25mg of Zebeta + HTC 6.5mg ?
Yes I have read that Zebeta is the best Beta-Blocker in the market. I thought it's the Zebeta that gave me side effects, but actually I have Anxiety and Depression and just started Efexor XR 75mg + Xanax 0.5mg.
Thanks again for help,
Michael
Actually, in Egypt we have a brand that contains 2.5/6.5 mg of the BB and the HCT respectively. and I think that there is another version of it (1.25mg/6.5) but I'm not sure. So I will start from tonight to reduce my Diltiazem from 120 to 90 and go to the dr after a week to see if the Norvasc 2.5/Zebeta is good for me.

My problem is that I want exercise and Beta-Blockers slow the heart rate. I hope that that small dose of zebeta has the same effect on my heart rate as the diltiazem, but with my current condition I can workout an hour without a break.
What do you think? :)
Michael
[QUOTE=cartner;3322716]flowergirl,

Thank you very much for your help. My blood pressure is 140/100 from Nov to the end of April or even after that. So you want me to wean off Diltiazem while starting to take 2.5mg Norvasc + 1.25mg of Zebeta + HTC 6.5mg ? then in 2 weeks I would be on the 5mg of Norvasc plus the 1.25mg of Zebeta + HTC 6.5mg ?
Yes I have read that Zebeta is the best Beta-Blocker in the market. I thought it's the Zebeta that gave me side effects, but actually I have Anxiety and Depression and just started Efexor XR 75mg + Xanax 0.5mg.
Thanks again for help,
Michael


I also suffer from seasonal depression. In fact, I took Effexor for a very short period of time but reacted badly to it. I'm not sure if this would help but I use full spectrum light in the areas where I work at home. I read somewhere that vitamin D is supposed to be helpful for depression as well as hbp. Since I have both (including anxiety) I take cod liver oil in the winter months. Ask your doctor about this though.

I take this as a supplement together with Coversyl and now Atacand (I've just been switched because of the annoying cough). By the way, my first few days on Coversyl, I got extremely agitated and nervous--something that hasn't happened in a while. Chances are though, it was a coincidence since it didn't happen again in six weeks.

All the best.
Mountainrain,

I have depression and anxiety all the year long. But in winter, when my blood pressure spikes, I become even more depressed. I tried both of Coversyl and Atacand, they caused a lot of bad side effects. My only hope is a combination between Zebeta, Norvasc and HCT.
I wonder how did you do with Efexor? it was the XR (extented release) version? I take 75mg only.
Thanks,
Michael
I try to do my best to find the right combination, after what I have experienced I think that my best combination is 2.5mg of Zebeta + 6.5mg of HCT + 2.5mg of Norvasc, with the possibility of increasing Norvasc to 5 mg and the HCT to 12.5 if needed. Of course I have to talk with my dr about that. I'm going to see him next Saturday, to check my doses of all the medications including Efexor.
About the cough, many of the people who experienced cough on ACEs would do fine on ARBs. My father had a very bad cough, all day long, when he was on ACEs and when he switched to ARBs (Cozaar and Atacand) it was greatly reduced.
Good luck and please let me know when you get better on Atacand.
Michael
Hi Michael,

[QUOTE]I think that my best combination is 2.5mg of Zebeta + 6.5mg of HCT + 2.5mg of Norvasc, with the possibility of increasing Norvasc to 5 mg and the HCT to 12.5 if needed. Of course I have to talk with my dr about that. I'm going to see him next Saturday, to check my doses of all the medications including Efexor

I hope you will post an update after your doctors' visit. :)

I read an article the other day about seasonal variations in blood pressure. It made me think of you. Apparently, regardless of where we live, be it warmer or colder climates, we are bound to experience an elevation in blood pressure in wintertime. All age groups are affected, including children. The reason for this is thought to be mainly the change in the environmental temperature. Our bodies react by constricting the blood vessels, which results in a decreased cardiac output. We are not as active. Urinary excretion of salt was found to be higher in the winter. This is attributed to an increased calorie intake due to the demand for higher calories needed for the body heat production. Interestingly, the variations in blood pressure are greater in thin people. It is thought that fat in obese people provides insulation and helps keep the body heat in. The variation in blood pressure in also higher in older people. The main thing to remember is that treatment strategies should account for these variations and the meds should be adjusted in the spring and fall. This article made me wonder about the recent elevations in my blood pressure. I needed more meds.

take care,
flowergirl