My Endo has me on 100,000 IU of vitamin D once a week. I've been on that dose for a year now. I'm not on a calcium supplement (which is needed in addition to the Forteo, or pamidronate, or Fosamax, or Actonel, to do their job adequately) because even just 500 mg of calcium a day constipates me and I can't handle that with Crohn's disease. I'm just not willing to risk aggravating the Crohn's and causing a serious flare. I'm at the point where I want to know whether the osteoporosis has advanced, or at least stayed the same. I'm not expecting a miracle of an improvement (tho it would be nice).