Discussions that mention pamidronate

Osteoporosis board


Well, you are still of child-bearing years so Forteo is out for the time being. That pretty much leaves you with Fosamax, Actonel and Boniva for oral medications. If your GI tract can't handle the Fosomax, Actonel or Boniva then there is the alternative of pamidronate or zolendronate (sp?) infusions. I'm a bit leery of the zolendronate but have had the pamidronate infusion. I have Crohn's disease so absolutely refuse to even try the oral bisphosphonates such as Fosamax and Actonel. With the infusion most all the risk of GI upset is nil. Usually it is a 2 hour drip. In my case I experienced some mild tingling of the lips and wrists so they immediately slowed the drip to a 4 hour drip and I had no other side effects occur. Depending on the dose used these can occur every 3 months, every 4 month or every 6 months. I believe the zolendronate is once a year. I'd rather have the smaller dose more often than one big dose - just in case. Forteo was approved shortly after my first pamidronate infusion and I opted to go with the Forteo instead because it works by encouraging new bone cell growth rather than slowing bone cell death as the bisphosphonates do.