Discussions that mention phenytoin

Inner Ear Disorders board


Quote from coryb:
I started taking some new medication about two weeks ago. It is called Trileptal.

Cory


Hi

Under---(on the Northwestern Univ web site(Prof Hain))-----

"Drug Treatment of Vertigo"

"Pharmacology"


......."Agents whose whose role is presently uncertain--sometimes successfully used in treatment of vertigo, although their use has not been studied extensively.".......

........."A sodium channel blocker, phenytoin (Dilantin), has also been recently reported to be protective against motion sickness (Knox et al, 1994). The author of this review has had no success in limited trials in patients with severe motion sickness unresponsive to the usual agents. Gabapentin (Neurontin), carbamazepine (Tegretol) and oxcarbazepine (Trileptal) are also sometimes successfully used in treatment of vertigo, although their use has not been studied extensively. Gabapentin has also been successfully used to suppress certain types of central nystagmus (Stahl et al, 1995). As these agents affect GABA, which is important in vertigo, an antivertigo effect is reasonable. Tegretol and Trileptal are particularly useful in paroxysmal disorders such as microvascular compression syndrome, and neuritis of the vestibular nerve. Recent agents have been developed for epilepsy which are glutamate antagonists, but at this writing, they have not been tried as treatments of vertigo. Anticonvulsants are promising agents for treatment of vertigo."........

In addition it is listed---under "migraine" treatment(on the Northwestern Univ site)

...."Carbamazepine (Tegretol) is not effective as a preventive (group 5). A related anticonvulsant, oxcarbazepine (Trileptal) has had some limited success in treating refractory migraine (only about 25% response, Krusz, 2000). "......

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