I was diagnosed several years ago that I have Osteoarthritis. I currently do not take any medication or anti-inflammatory because I am Asthmatic and on so many other medications. I have had in inflammation in most of muscles for the past 2 1/2 years making it very difficult to sleep at night. I was given two cortisone shots two years ago and it did nothing. I have been on Prednisone, Prednisolone and nothing takes away the inflammation. Does anyone know if inflammation in the muscles could be caused by Arthritis?