I was put on Remeron last year as a combo with the 20mg of prozac that I have been taking for years, with no weight gain. I gained about 20 lbs in 6 weeks! It was unbelievable. I was hungry all the time, and definitely ate a lot more, but it was also terrible bloating. Even my fingers swelled up and my rings wouldn't fit anymore. So I stopped taking it and within a month the weight was gone, without even dieting. So I think it somehow changes your metabolism and causes you to retain water so you swell up. The extra eating certainly was a factor too. It just wasn't the medication for me I guess.